Kitteringham NR - Search Results

1

Structural requirements for bioactivation of anticonvulsants to cytotoxic metabolites in vitro.

Riley RJ, Kitteringham NR, Park BK. Riley RJ, et al. Among authors: kitteringham nr. Br J Clin Pharmacol. 1989 Oct;28(4):482-7. doi: 10.1111/j.1365-2125.1989.tb03530.x. Br J Clin Pharmacol. 1989. PMID: 2590607 Free PMC article.

2

Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.

Park BK, Pirmohamed M, Kitteringham NR. Park BK, et al. Among authors: kitteringham nr. Br J Clin Pharmacol. 1992 Nov;34(5):377-95. doi: 10.1111/j.1365-2125.1992.tb05647.x. Br J Clin Pharmacol. 1992. PMID: 1467132 Free PMC article. Review. No abstract available.

3

The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes.

Pirmohamed M, Kitteringham NR, Breckenridge AM, Park BK. Pirmohamed M, et al. Among authors: kitteringham nr. Biochem Pharmacol. 1992 Dec 15;44(12):2307-14. doi: 10.1016/0006-2952(92)90674-8. Biochem Pharmacol. 1992. PMID: 1472096

4

Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.

Pirmohamed M, Kitteringham NR, Breckenridge AM, Park BK. Pirmohamed M, et al. Among authors: kitteringham nr. Br J Clin Pharmacol. 1992 Feb;33(2):183-6. doi: 10.1111/j.1365-2125.1992.tb04022.x. Br J Clin Pharmacol. 1992. PMID: 1550698 Free PMC article.

5

The mechanism of bioactivation and antigen formation of amodiaquine in the rat.

Harrison AC, Kitteringham NR, Clarke JB, Park BK. Harrison AC, et al. Among authors: kitteringham nr. Biochem Pharmacol. 1992 Apr 1;43(7):1421-30. doi: 10.1016/0006-2952(92)90198-r. Biochem Pharmacol. 1992. PMID: 1567466

6

An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro.

Pirmohamed M, Kitteringham NR, Guenthner TM, Breckenridge AM, Park BK. Pirmohamed M, et al. Among authors: kitteringham nr. Biochem Pharmacol. 1992 Apr 15;43(8):1675-82. doi: 10.1016/0006-2952(92)90696-g. Biochem Pharmacol. 1992. PMID: 1575766

7

Idiosyncratic reactions to antidepressants: a review of the possible mechanisms and predisposing factors.

Pirmohamed M, Kitteringham NR, Park BK. Pirmohamed M, et al. Among authors: kitteringham nr. Pharmacol Ther. 1992;53(1):105-25. doi: 10.1016/0163-7258(92)90046-3. Pharmacol Ther. 1992. PMID: 1641399 Review.

8

Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.

Riley RJ, Roberts P, Coleman MD, Kitteringham NR, Park BK. Riley RJ, et al. Among authors: kitteringham nr. Br J Clin Pharmacol. 1990 Sep;30(3):417-26. doi: 10.1111/j.1365-2125.1990.tb03793.x. Br J Clin Pharmacol. 1990. PMID: 2223420 Free PMC article.

9

Assessment of enzyme induction and enzyme inhibition in humans: toxicological implications.

Park BK, Kitteringham NR. Park BK, et al. Among authors: kitteringham nr. Xenobiotica. 1990 Nov;20(11):1171-85. doi: 10.3109/00498259009046837. Xenobiotica. 1990. PMID: 2275213 Review.

10

Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes.

Riley RJ, Roberts P, Kitteringham NR, Park BK. Riley RJ, et al. Among authors: kitteringham nr. Biochem Pharmacol. 1990 Jun 15;39(12):1951-8. doi: 10.1016/0006-2952(90)90614-q. Biochem Pharmacol. 1990. PMID: 2353936

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