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Page 1
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment.
Bermejo IA, Navo CD, Castro-López J, Guerreiro A, Jiménez-Moreno E, Sánchez Fernández EM, García-Martín F, Hinou H, Nishimura SI, García Fernández JM, Mellet CO, Avenoza A, Busto JH, Bernardes GJL, Hurtado-Guerrero R, Peregrina JM, Corzana F. Bermejo IA, et al. Chem Sci. 2020 Mar 27;11(15):3996-4006. doi: 10.1039/c9sc06334j. Chem Sci. 2020. PMID: 34122869 Free PMC article.
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.
Somovilla VJ, Bermejo IA, Albuquerque IS, Martínez-Sáez N, Castro-López J, García-Martín F, Compañón I, Hinou H, Nishimura SI, Jiménez-Barbero J, Asensio JL, Avenoza A, Busto JH, Hurtado-Guerrero R, Peregrina JM, Bernardes GJL, Corzana F. Somovilla VJ, et al. Among authors: bermejo ia. J Am Chem Soc. 2017 Dec 20;139(50):18255-18261. doi: 10.1021/jacs.7b09447. Epub 2017 Dec 12. J Am Chem Soc. 2017. PMID: 29166012 Free article.
Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment.
Martínez-Sáez N, Supekar NT, Wolfert MA, Bermejo IA, Hurtado-Guerrero R, Asensio JL, Jiménez-Barbero J, Busto JH, Avenoza A, Boons GJ, Peregrina JM, Corzana F. Martínez-Sáez N, et al. Among authors: bermejo ia. Chem Sci. 2016 Mar 1;7(3):2294-2301. doi: 10.1039/c5sc04039f. Epub 2015 Dec 15. Chem Sci. 2016. PMID: 29910919 Free PMC article.
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition.
Bermejo IA, Usabiaga I, Compañón I, Castro-López J, Insausti A, Fernández JA, Avenoza A, Busto JH, Jiménez-Barbero J, Asensio JL, Peregrina JM, Jiménez-Osés G, Hurtado-Guerrero R, Cocinero EJ, Corzana F. Bermejo IA, et al. J Am Chem Soc. 2018 Aug 8;140(31):9952-9960. doi: 10.1021/jacs.8b04801. Epub 2018 Jul 30. J Am Chem Soc. 2018. PMID: 30004703
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.
Macías-León J , Bermejo IA , Asín A , García-García A , Compañón I , Jiménez-Moreno E , Coelho H , Mangini V , Albuquerque IS , Marcelo F , Asensio JL , Bernardes GJL , Joshi HJ , Fiammengo R , Blixt O , Hurtado-Guerrero R , Corzana F . Macías-León J , et al. Among authors: bermejo ia. Chem Commun (Camb). 2020 Dec 8;56(96):15137-15140. doi: 10.1039/d0cc06349e. Chem Commun (Camb). 2020. PMID: 33211039
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer.
Amedei A, Asadzadeh F, Papi F, Vannucchi MG, Ferrucci V, Bermejo IA, Fragai M, De Almeida CV, Cerofolini L, Giuntini S, Bombaci M, Pesce E, Niccolai E, Natali F, Guarini E, Gabel F, Traini C, Catarinicchia S, Ricci F, Orzalesi L, Berti F, Corzana F, Zollo M, Grifantini R, Nativi C. Amedei A, et al. Among authors: bermejo ia. iScience. 2020 Jun 26;23(6):101250. doi: 10.1016/j.isci.2020.101250. Epub 2020 Jun 6. iScience. 2020. PMID: 32629615 Free PMC article.
Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling.
Unione L, Ammerlaan ANA, Bosman GP, Uslu E, Liang R, Broszeit F, van der Woude R, Liu Y, Ma S, Liu L, Gómez-Redondo M, Bermejo IA, Valverde P, Diercks T, Ardá A, de Vries RP, Boons GJ. Unione L, et al. Among authors: bermejo ia. Nat Commun. 2024 Apr 6;15(1):2979. doi: 10.1038/s41467-024-47344-y. Nat Commun. 2024. PMID: 38582892 Free PMC article.
Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses.
Bermejo IA, Guerreiro A, Eguskiza A, Martínez-Sáez N, Lazaris FS, Asín A, Somovilla VJ, Compañón I, Raju TK, Tadic S, Garrido P, García-Sanmartín J, Mangini V, Grosso AS, Marcelo F, Avenoza A, Busto JH, García-Martín F, Hurtado-Guerrero R, Peregrina JM, Bernardes GJL, Martínez A, Fiammengo R, Corzana F. Bermejo IA, et al. JACS Au. 2023 Nov 21;4(1):150-163. doi: 10.1021/jacsau.3c00587. eCollection 2024 Jan 22. JACS Au. 2023. PMID: 38274250 Free PMC article.
11 results