Chen F - Search Results

1

Cytotoxicity profile of novel sterically hindered platinum(II) complexes with (1R,2R)-N(1),N(2)-dibutyl-1,2-diaminocyclohexane.

Zhang H, Gou S, Zhao J, Chen F, Xu G, Liu X. Zhang H, et al. Among authors: chen f. Eur J Med Chem. 2015;96:187-95. doi: 10.1016/j.ejmech.2015.04.019. Epub 2015 Apr 8. Eur J Med Chem. 2015. PMID: 25874342

2

DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.

Zhang LB, Qiang L, Chen FH, Wu T, Rong JJ, Zhao Q, Zou MJ, Yang Z, You QD, Li ZY, Wu YL, Guo QL. Zhang LB, et al. Eur J Pharmacol. 2011 Jan 25;651(1-3):33-40. doi: 10.1016/j.ejphar.2010.10.067. Epub 2010 Nov 18. Eur J Pharmacol. 2011. PMID: 21093431

3

Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it.

Sun HP, Zhu J, Chen FH, Zhang SL, Zhang Y, You QD. Sun HP, et al. Eur J Med Chem. 2011 Sep;46(9):3942-52. doi: 10.1016/j.ejmech.2011.05.066. Epub 2011 Jun 25. Eur J Med Chem. 2011. PMID: 21708416

4

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

Sun H, Chen F, Wang X, Liu Z, Yang Q, Zhang X, Zhu J, Qiang L, Guo Q, You Q. Sun H, et al. Among authors: chen f. Eur J Med Chem. 2012 May;51:110-23. doi: 10.1016/j.ejmech.2012.02.029. Epub 2012 Mar 3. Eur J Med Chem. 2012. PMID: 22472167

5

Study on Antitumor Platinum(II) Complexes of Chiral Diamines with Dicyclic Species as Steric Hindrance.

Liu F, Gou S, Chen F, Fang L, Zhao J. Liu F, et al. Among authors: chen f. J Med Chem. 2015 Aug 27;58(16):6368-77. doi: 10.1021/jm501952r. Epub 2015 Aug 18. J Med Chem. 2015. PMID: 26247573

6

Study on the cytotoxic activity of platinum(II) complexes of (1R,2R)-N(1)-cyclopentyl-1,2-cyclohexanediamine with substituted malonate derivatives.

Zhou Z, Chen F, Xu G, Gou S. Zhou Z, et al. Among authors: chen f. Bioorg Med Chem Lett. 2016 Jan 15;26(2):322-327. doi: 10.1016/j.bmcl.2015.12.019. Epub 2015 Dec 8. Bioorg Med Chem Lett. 2016. PMID: 26711148

7

Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes.

Yu H, Gou S, Wang Z, Chen F, Fang L. Yu H, et al. Among authors: chen f. Eur J Med Chem. 2016 May 23;114:141-52. doi: 10.1016/j.ejmech.2016.02.060. Epub 2016 Feb 27. Eur J Med Chem. 2016. PMID: 26974381

8

Design, Synthesis, and Biological Features of Platinum(II) Complexes with Rigid Steric Hindrance.

Wang Z, Yu H, Gou S, Chen F, Fang L. Wang Z, et al. Among authors: chen f. Inorg Chem. 2016 May 2;55(9):4519-28. doi: 10.1021/acs.inorgchem.6b00361. Epub 2016 Apr 13. Inorg Chem. 2016. PMID: 27074104

9

Oleanolic acid-NO donor-platinum(II) trihybrid molecules: Targeting cytotoxicity on hepatoma cells with combined action mode and good safety.

Fang L, Feng M, Chen F, Liu X, Shen H, Zhao J, Gou S. Fang L, et al. Among authors: chen f. Bioorg Med Chem. 2016 Oct 1;24(19):4611-4619. doi: 10.1016/j.bmc.2016.07.066. Epub 2016 Jul 30. Bioorg Med Chem. 2016. PMID: 27501909

10

A CK2-targeted Pt(IV) prodrug to disrupt DNA damage response.

Chen F, Huang X, Wu M, Gou S, Hu W. Chen F, et al. Cancer Lett. 2017 Jan 28;385:168-178. doi: 10.1016/j.canlet.2016.10.026. Epub 2016 Oct 25. Cancer Lett. 2017. PMID: 27793693

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