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Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
Rönn T, Volkov P, Gillberg L, Kokosar M, Perfilyev A, Jacobsen AL, Jørgensen SW, Brøns C, Jansson PA, Eriksson KF, Pedersen O, Hansen T, Groop L, Stener-Victorin E, Vaag A, Nilsson E, Ling C. Rönn T, et al. Among authors: perfilyev a. Hum Mol Genet. 2015 Jul 1;24(13):3792-813. doi: 10.1093/hmg/ddv124. Epub 2015 Apr 10. Hum Mol Genet. 2015. PMID: 25861810
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
Nilsson E, Jansson PA, Perfilyev A, Volkov P, Pedersen M, Svensson MK, Poulsen P, Ribel-Madsen R, Pedersen NL, Almgren P, Fadista J, Rönn T, Klarlund Pedersen B, Scheele C, Vaag A, Ling C. Nilsson E, et al. Among authors: perfilyev a. Diabetes. 2014 Sep;63(9):2962-76. doi: 10.2337/db13-1459. Epub 2014 May 8. Diabetes. 2014. PMID: 24812430
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
Dahlman I, Sinha I, Gao H, Brodin D, Thorell A, Rydén M, Andersson DP, Henriksson J, Perfilyev A, Ling C, Dahlman-Wright K, Arner P. Dahlman I, et al. Among authors: perfilyev a. Int J Obes (Lond). 2015 Jun;39(6):910-9. doi: 10.1038/ijo.2015.31. Epub 2015 Mar 18. Int J Obes (Lond). 2015. PMID: 25783037
Epigenetic programming of adipose-derived stem cells in low birthweight individuals.
Broholm C, Olsson AH, Perfilyev A, Hansen NS, Schrölkamp M, Strasko KS, Scheele C, Ribel-Madsen R, Mortensen B, Jørgensen SW, Ling C, Vaag A. Broholm C, et al. Among authors: perfilyev a. Diabetologia. 2016 Dec;59(12):2664-2673. doi: 10.1007/s00125-016-4099-9. Epub 2016 Sep 14. Diabetologia. 2016. PMID: 27627980
44 results