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Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia.
Du W, Tao Y, Deng WT, Zhu P, Li J, Dai X, Zhang Y, Shi W, Liu X, Chiodo VA, Ding XQ, Zhao C, Michalakis S, Biel M, Zhang Z, Qu J, Hauswirth WW, Pang JJ. Du W, et al. Among authors: pang jj. Hum Mol Genet. 2015 Jul 1;24(13):3699-707. doi: 10.1093/hmg/ddv114. Epub 2015 Apr 8. Hum Mol Genet. 2015. PMID: 25855802 Free PMC article.
Achromatopsia as a potential candidate for gene therapy.
Pang JJ, Alexander J, Lei B, Deng W, Zhang K, Li Q, Chang B, Hauswirth WW. Pang JJ, et al. Adv Exp Med Biol. 2010;664:639-46. doi: 10.1007/978-1-4419-1399-9_73. Adv Exp Med Biol. 2010. PMID: 20238068 Free PMC article.
Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.
Zhang Y, Deng WT, Du W, Zhu P, Li J, Xu F, Sun J, Gerstner CD, Baehr W, Boye SL, Zhao C, Hauswirth WW, Pang JJ. Zhang Y, et al. Among authors: pang jj. Sci Rep. 2017 Jul 27;7(1):6690. doi: 10.1038/s41598-017-06982-7. Sci Rep. 2017. PMID: 28751656 Free PMC article.
Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse.
Deng WT, Sakurai K, Kolandaivelu S, Kolesnikov AV, Dinculescu A, Li J, Zhu P, Liu X, Pang J, Chiodo VA, Boye SL, Chang B, Ramamurthy V, Kefalov VJ, Hauswirth WW. Deng WT, et al. J Neurosci. 2013 Jul 17;33(29):11745-53. doi: 10.1523/JNEUROSCI.1536-13.2013. J Neurosci. 2013. PMID: 23864662 Free PMC article.
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.
Pang JJ, Chang B, Kumar A, Nusinowitz S, Noorwez SM, Li J, Rani A, Foster TC, Chiodo VA, Doyle T, Li H, Malhotra R, Teusner JT, McDowell JH, Min SH, Li Q, Kaushal S, Hauswirth WW. Pang JJ, et al. Mol Ther. 2006 Mar;13(3):565-72. doi: 10.1016/j.ymthe.2005.09.001. Epub 2005 Oct 11. Mol Ther. 2006. PMID: 16223604 Free article.
136 results