Teo AK - Search Results

1

PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.

Teo AK, Tsuneyoshi N, Hoon S, Tan EK, Stanton LW, Wright CV, Dunn NR. Teo AK, et al. Stem Cell Reports. 2015 Apr 14;4(4):578-90. doi: 10.1016/j.stemcr.2015.02.015. Epub 2015 Apr 2. Stem Cell Reports. 2015. PMID: 25843046 Free PMC article.

2

Pluripotency factors regulate definitive endoderm specification through eomesodermin.

Teo AK, Arnold SJ, Trotter MW, Brown S, Ang LT, Chng Z, Robertson EJ, Dunn NR, Vallier L. Teo AK, et al. Genes Dev. 2011 Feb 1;25(3):238-50. doi: 10.1101/gad.607311. Epub 2011 Jan 18. Genes Dev. 2011. PMID: 21245162 Free PMC article.

3

Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.

Teo AK, Lau HH, Valdez IA, Dirice E, Tjora E, Raeder H, Kulkarni RN. Teo AK, et al. Stem Cell Reports. 2016 Mar 8;6(3):357-67. doi: 10.1016/j.stemcr.2016.01.007. Epub 2016 Feb 11. Stem Cell Reports. 2016. PMID: 26876668 Free PMC article.

4

Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation.

Valdez IA, Dirice E, Gupta MK, Shirakawa J, Teo AKK, Kulkarni RN. Valdez IA, et al. Cell Rep. 2016 Apr 19;15(3):460-470. doi: 10.1016/j.celrep.2016.03.036. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068459 Free PMC article.

5

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells.

Ng NHJ, Jasmen JB, Lim CS, Lau HH, Krishnan VG, Kadiwala J, Kulkarni RN, Ræder H, Vallier L, Hoon S, Teo AKK. Ng NHJ, et al. iScience. 2019 Jun 28;16:192-205. doi: 10.1016/j.isci.2019.05.032. Epub 2019 May 27. iScience. 2019. PMID: 31195238 Free PMC article.

6

New insights into human beta cell biology using human pluripotent stem cells.

Amirruddin NS, Low BSJ, Lee KO, Tai ES, Teo AKK. Amirruddin NS, et al. Semin Cell Dev Biol. 2020 Jul;103:31-40. doi: 10.1016/j.semcdb.2019.11.004. Epub 2019 Nov 19. Semin Cell Dev Biol. 2020. PMID: 31757584 Review.

7

Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors.

Loo LSW, Vethe H, Soetedjo AAP, Paulo JA, Jasmen J, Jackson N, Bjørlykke Y, Valdez IA, Vaudel M, Barsnes H, Gygi SP, Raeder H, Teo AKK, Kulkarni RN. Loo LSW, et al. Stem Cells. 2020 Apr;38(4):542-555. doi: 10.1002/stem.3135. Epub 2020 Jan 22. Stem Cells. 2020. PMID: 31828876 Free PMC article.

8

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells.

Loo LSW, Soetedjo AAP, Lau HH, Ng NHJ, Ghosh S, Nguyen L, Krishnan VG, Choi H, Roca X, Hoon S, Teo AKK. Loo LSW, et al. Cell Death Dis. 2020 May 18;11(5):378. doi: 10.1038/s41419-020-2589-7. Cell Death Dis. 2020. PMID: 32424151 Free PMC article.

9

Metformin Perturbs Pancreatic Differentiation From Human Embryonic Stem Cells.

Nguyen L, Lim LY, Ding SSL, Amirruddin NS, Hoon S, Chan SY, Teo AKK. Nguyen L, et al. Diabetes. 2021 Aug;70(8):1689-1702. doi: 10.2337/db20-0722. Epub 2021 May 6. Diabetes. 2021. PMID: 33958328

10

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells.

Low BSJ, Lim CS, Ding SSL, Tan YS, Ng NHJ, Krishnan VG, Ang SF, Neo CWY, Verma CS, Hoon S, Lim SC, Tai ES, Teo AKK. Low BSJ, et al. Nat Commun. 2021 May 25;12(1):3133. doi: 10.1038/s41467-021-22843-4. Nat Commun. 2021. PMID: 34035238 Free PMC article.

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