Yang CH - Search Results

1

Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition.

Yi JM, Zhang XF, Huan XJ, Song SS, Wang W, Tian QT, Sun YM, Chen Y, Ding J, Wang YQ, Yang CH, Miao ZH. Yi JM, et al. Among authors: yang ch. Oncotarget. 2015 Apr 20;6(11):8960-73. doi: 10.18632/oncotarget.3264. Oncotarget. 2015. PMID: 25840421 Free PMC article.

2

Novel indole alpha-methylene-gamma-lactones as potent inhibitors for AKT-mTOR signaling pathway kinases.

Ding H, Zhang C, Wu X, Yang C, Zhang X, Ding J, Xie Y. Ding H, et al. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4799-802. doi: 10.1016/j.bmcl.2005.07.050. Bioorg Med Chem Lett. 2005. PMID: 16143526

3

Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents.

Wu M, Sun Q, Yang C, Chen D, Ding J, Chen Y, Lin L, Xie Y. Wu M, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):869-73. doi: 10.1016/j.bmcl.2006.11.060. Epub 2006 Nov 29. Bioorg Med Chem Lett. 2007. PMID: 17174089

4

S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.

Zhang C, Yang N, Yang CH, Ding HS, Luo C, Zhang Y, Wu MJ, Zhang XW, Shen X, Jiang HL, Meng LH, Ding J. Zhang C, et al. Among authors: yang ch, yang n. PLoS One. 2009;4(3):e4881. doi: 10.1371/journal.pone.0004881. Epub 2009 Mar 18. PLoS One. 2009. PMID: 19293927 Free PMC article.

5

Direct palladium-catalyzed arylations of aryl bromides with 2/9-substituted pyrimido[5,4-b]indolizines.

Jiang M, Li T, Meng L, Yang C, Xie Y, Ding J. Jiang M, et al. J Comb Chem. 2009 Sep-Oct;11(5):806-8. doi: 10.1021/cc800162k. J Comb Chem. 2009. PMID: 19645499

6

WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.

Li T, Wang J, Wang X, Yang N, Chen SM, Tong LJ, Yang CH, Meng LH, Ding J. Li T, et al. Among authors: yang ch, yang n. J Pharmacol Exp Ther. 2010 Sep 1;334(3):830-8. doi: 10.1124/jpet.110.167940. Epub 2010 Jun 3. J Pharmacol Exp Ther. 2010. PMID: 20522531

7

Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.

He JX, Yang CH, Miao ZH. He JX, et al. Among authors: yang ch. Acta Pharmacol Sin. 2010 Sep;31(9):1172-80. doi: 10.1038/aps.2010.103. Epub 2010 Aug 2. Acta Pharmacol Sin. 2010. PMID: 20676117 Free PMC article. Review.

8

Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.

Wang YQ, Li XH, He Q, Chen Y, Xie YY, Ding J, Miao ZH, Yang CH. Wang YQ, et al. Among authors: yang ch. Eur J Med Chem. 2011 Dec;46(12):5878-84. doi: 10.1016/j.ejmech.2011.09.050. Epub 2011 Oct 4. Eur J Med Chem. 2011. PMID: 22000922

9

Discovery and bioactivity of 4-(2-arylpyrido[3',2':3,4]pyrrolo[1,2-f][1,2,4]triazin-4-yl) morpholine derivatives as novel PI3K inhibitors.

Wang J, Wang X, Chen Y, Chen S, Chen G, Tong L, Meng L, Xie Y, Ding J, Yang C. Wang J, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):339-42. doi: 10.1016/j.bmcl.2011.11.003. Epub 2011 Nov 9. Bioorg Med Chem Lett. 2012. PMID: 22130133

10

Copper-mediated, palladium-catalyzed cross-coupling of 3-iodochromones, thiochromones, and quinolones with ethyl bromodifluoroacetate.

Han X, Yue Z, Zhang X, He Q, Yang C. Han X, et al. J Org Chem. 2013 May 17;78(10):4850-6. doi: 10.1021/jo400412k. Epub 2013 Apr 30. J Org Chem. 2013. PMID: 23594098

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