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Page 1
Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.
Lanvers-Kaminsky C, Sprowl JA, Malath I, Deuster D, Eveslage M, Schlatter E, Mathijssen RH, Boos J, Jürgens H, Am Zehnhoff-Dinnesen AG, Sparreboom A, Ciarimboli G. Lanvers-Kaminsky C, et al. Among authors: schlatter e. Pharmacogenomics. 2015;16(4):323-32. doi: 10.2217/pgs.14.182. Pharmacogenomics. 2015. PMID: 25823781 Free PMC article.
Regulation of organic cation transport.
Ciarimboli G, Schlatter E. Ciarimboli G, et al. Among authors: schlatter e. Pflugers Arch. 2005 Feb;449(5):423-41. doi: 10.1007/s00424-004-1355-5. Epub 2004 Nov 16. Pflugers Arch. 2005. PMID: 15688244 Review.
Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.
Ciarimboli G, Deuster D, Knief A, Sperling M, Holtkamp M, Edemir B, Pavenstädt H, Lanvers-Kaminsky C, am Zehnhoff-Dinnesen A, Schinkel AH, Koepsell H, Jürgens H, Schlatter E. Ciarimboli G, et al. Among authors: schlatter e. Am J Pathol. 2010 Mar;176(3):1169-80. doi: 10.2353/ajpath.2010.090610. Epub 2010 Jan 28. Am J Pathol. 2010. PMID: 20110413 Free PMC article.
Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.
Ciarimboli G, Lancaster CS, Schlatter E, Franke RM, Sprowl JA, Pavenstädt H, Massmann V, Guckel D, Mathijssen RH, Yang W, Pui CH, Relling MV, Herrmann E, Sparreboom A. Ciarimboli G, et al. Among authors: schlatter e. Clin Cancer Res. 2012 Feb 15;18(4):1101-8. doi: 10.1158/1078-0432.CCR-11-2503. Epub 2012 Jan 5. Clin Cancer Res. 2012. PMID: 22223530 Free PMC article.
Cisplatin-induced renal injury is independently mediated by OCT2 and p53.
Sprowl JA, Lancaster CS, Pabla N, Hermann E, Kosloske AM, Gibson AA, Li L, Zeeh D, Schlatter E, Janke LJ, Ciarimboli G, Sparreboom A. Sprowl JA, et al. Among authors: schlatter e. Clin Cancer Res. 2014 Aug 1;20(15):4026-35. doi: 10.1158/1078-0432.CCR-14-0319. Epub 2014 Jun 10. Clin Cancer Res. 2014. PMID: 24916697 Free PMC article.
A phosphotyrosine switch regulates organic cation transporters.
Sprowl JA, Ong SS, Gibson AA, Hu S, Du G, Lin W, Li L, Bharill S, Ness RA, Stecula A, Offer SM, Diasio RB, Nies AT, Schwab M, Cavaletti G, Schlatter E, Ciarimboli G, Schellens JHM, Isacoff EY, Sali A, Chen T, Baker SD, Sparreboom A, Pabla N. Sprowl JA, et al. Among authors: schlatter e. Nat Commun. 2016 Mar 16;7:10880. doi: 10.1038/ncomms10880. Nat Commun. 2016. PMID: 26979622 Free PMC article.
An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection.
Hucke A, Rinschen MM, Bauer OB, Sperling M, Karst U, Köppen C, Sommer K, Schröter R, Ceresa C, Chiorazzi A, Canta A, Semperboni S, Marmiroli P, Cavaletti G, Schlatt S, Schlatter E, Pavenstädt H, Heitplatz B, Van Marck V, Sparreboom A, Barz V, Knief A, Deuster D, Zehnhoff-Dinnesen AA, Ciarimboli G. Hucke A, et al. Among authors: schlatter e. Arch Toxicol. 2019 Oct;93(10):2835-2848. doi: 10.1007/s00204-019-02557-9. Epub 2019 Sep 6. Arch Toxicol. 2019. PMID: 31493026
Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.
Hu S, Leblanc AF, Gibson AA, Hong KW, Kim JY, Janke LJ, Li L, Vasilyeva A, Finkelstein DB, Sprowl JA, Sweet DH, Schlatter E, Ciarimboli G, Schellens J, Baker SD, Pabla N, Sparreboom A. Hu S, et al. Among authors: schlatter e. Clin Transl Sci. 2017 Sep;10(5):412-420. doi: 10.1111/cts.12480. Epub 2017 Jul 8. Clin Transl Sci. 2017. PMID: 28689374 Free PMC article.
181 results