Luthra A - Search Results

1

Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN.

Anand A, LeDoyt M, Karanian C, Luthra A, Koszelak-Rosenblum M, Malkowski MG, Puthenveetil R, Vinogradova O, Radolf JD. Anand A, et al. Among authors: luthra a. J Biol Chem. 2015 May 8;290(19):12313-31. doi: 10.1074/jbc.M114.629188. Epub 2015 Mar 24. J Biol Chem. 2015. PMID: 25805501 Free PMC article.

2

TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein.

Desrosiers DC, Anand A, Luthra A, Dunham-Ems SM, LeDoyt M, Cummings MA, Eshghi A, Cameron CE, Cruz AR, Salazar JC, Caimano MJ, Radolf JD. Desrosiers DC, et al. Among authors: luthra a. Mol Microbiol. 2011 Jun;80(6):1496-515. doi: 10.1111/j.1365-2958.2011.07662.x. Epub 2011 Apr 27. Mol Microbiol. 2011. PMID: 21488980 Free PMC article.

3

The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.

Luthra A, Zhu G, Desrosiers DC, Eggers CH, Mulay V, Anand A, McArthur FA, Romano FB, Caimano MJ, Heuck AP, Malkowski MG, Radolf JD. Luthra A, et al. J Biol Chem. 2011 Dec 2;286(48):41656-41668. doi: 10.1074/jbc.M111.305284. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965687 Free PMC article.

4

TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure.

Anand A, Luthra A, Dunham-Ems S, Caimano MJ, Karanian C, LeDoyt M, Cruz AR, Salazar JC, Radolf JD. Anand A, et al. Among authors: luthra a. J Bacteriol. 2012 May;194(9):2321-33. doi: 10.1128/JB.00101-12. Epub 2012 Mar 2. J Bacteriol. 2012. PMID: 22389487 Free PMC article.

5

The major outer sheath protein (Msp) of Treponema denticola has a bipartite domain architecture and exists as periplasmic and outer membrane-spanning conformers.

Anand A, Luthra A, Edmond ME, Ledoyt M, Caimano MJ, Radolf JD. Anand A, et al. Among authors: luthra a. J Bacteriol. 2013 May;195(9):2060-71. doi: 10.1128/JB.00078-13. Epub 2013 Mar 1. J Bacteriol. 2013. PMID: 23457251 Free PMC article.

6

A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.

Luthra A, Anand A, Hawley KL, LeDoyt M, La Vake CJ, Caimano MJ, Cruz AR, Salazar JC, Radolf JD. Luthra A, et al. J Bacteriol. 2015 Jun;197(11):1906-20. doi: 10.1128/JB.00086-15. Epub 2015 Mar 30. J Bacteriol. 2015. PMID: 25825429 Free PMC article.

7

Treponema pallidum in Gel Microdroplets: A Method for Topological Analysis of BamA (TP0326) and Localization of Rare Outer Membrane Proteins.

Luthra A, Anand A, Radolf JD. Luthra A, et al. Methods Mol Biol. 2015;1329:67-75. doi: 10.1007/978-1-4939-2871-2_6. Methods Mol Biol. 2015. PMID: 26427677

8

Structural modeling and physicochemical characterization provide evidence that P66 forms a β-barrel in the Borrelia burgdorferi outer membrane.

Kenedy MR, Luthra A, Anand A, Dunn JP, Radolf JD, Akins DR. Kenedy MR, et al. Among authors: luthra a. J Bacteriol. 2014 Feb;196(4):859-72. doi: 10.1128/JB.01236-13. Epub 2013 Dec 6. J Bacteriol. 2014. PMID: 24317399 Free PMC article.

9

Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.

Bauer WJ, Luthra A, Zhu G, Radolf JD, Malkowski MG, Caimano MJ. Bauer WJ, et al. Among authors: luthra a. J Struct Biol. 2015 Oct;192(1):48-58. doi: 10.1016/j.jsb.2015.08.013. Epub 2015 Aug 28. J Struct Biol. 2015. PMID: 26321039 Free PMC article.

10

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.

Luthra A, Montezuma-Rusca JM, La Vake CJ, LeDoyt M, Delgado KN, Davenport TC, Fiel-Gan M, Caimano MJ, Radolf JD, Hawley KL. Luthra A, et al. PLoS Pathog. 2020 Sep 16;16(9):e1008871. doi: 10.1371/journal.ppat.1008871. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32936831 Free PMC article.

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