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Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN.
Anand A, LeDoyt M, Karanian C, Luthra A, Koszelak-Rosenblum M, Malkowski MG, Puthenveetil R, Vinogradova O, Radolf JD. Anand A, et al. Among authors: ledoyt m. J Biol Chem. 2015 May 8;290(19):12313-31. doi: 10.1074/jbc.M114.629188. Epub 2015 Mar 24. J Biol Chem. 2015. PMID: 25805501 Free PMC article.
Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spirochete.
Kumar S, Caimano MJ, Anand A, Dey A, Hawley KL, LeDoyt ME, La Vake CJ, Cruz AR, Ramirez LG, Paštěková L, Bezsonova I, Šmajs D, Salazar JC, Radolf JD. Kumar S, et al. Among authors: ledoyt me. mBio. 2018 Jun 12;9(3):e01006-18. doi: 10.1128/mBio.01006-18. mBio. 2018. PMID: 29895642 Free PMC article.
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
Luthra A, Montezuma-Rusca JM, La Vake CJ, LeDoyt M, Delgado KN, Davenport TC, Fiel-Gan M, Caimano MJ, Radolf JD, Hawley KL. Luthra A, et al. Among authors: ledoyt m. PLoS Pathog. 2020 Sep 16;16(9):e1008871. doi: 10.1371/journal.ppat.1008871. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32936831 Free PMC article.