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The potential of lactulose and melibiose, two novel trehalase-indigestible and autophagy-inducing disaccharides, for polyQ-mediated neurodegenerative disease treatment.
Lee GC, Lin CH, Tao YC, Yang JM, Hsu KC, Huang YJ, Huang SH, Kung PJ, Chen WL, Wang CM, Wu YR, Chen CM, Lin JY, Hsieh-Li HM, Lee-Chen GJ. Lee GC, et al. Among authors: lee chen gj. Neurotoxicology. 2015 May;48:120-30. doi: 10.1016/j.neuro.2015.03.009. Epub 2015 Mar 20. Neurotoxicology. 2015. PMID: 25800379
Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis.
Lee LC, Chen CM, Chen FL, Lin PY, Hsiao YC, Wang PR, Su MT, Hsieh-Li HM, Hwang JC, Wu CH, Lee GC, Singh S, Lin Y, Hsieh SY, Lee-Chen GJ, Lin JY. Lee LC, et al. Among authors: lee gc, lee chen gj. Clin Chim Acta. 2009 Feb;400(1-2):56-62. doi: 10.1016/j.cca.2008.10.013. Epub 2008 Oct 30. Clin Chim Acta. 2009. PMID: 19014922
Role of the CCAAT-binding protein NFY in SCA17 pathogenesis.
Lee LC, Chen CM, Wang HC, Hsieh HH, Chiu IS, Su MT, Hsieh-Li HM, Wu CH, Lee GC, Lee-Chen GJ, Lin JY. Lee LC, et al. Among authors: lee gc, lee chen gj. PLoS One. 2012;7(4):e35302. doi: 10.1371/journal.pone.0035302. Epub 2012 Apr 17. PLoS One. 2012. PMID: 22530004 Free PMC article.
Novel compound VB-037 inhibits Aβ aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK-mediated inflammation in cell models for Alzheimer's disease.
Chiu YJ, Hsieh YH, Lin TH, Lee GC, Hsieh-Li HM, Sun YC, Chen CM, Chang KH, Lee-Chen GJ. Chiu YJ, et al. Among authors: lee gc, lee chen gj. Neurochem Int. 2019 May;125:175-186. doi: 10.1016/j.neuint.2019.01.021. Epub 2019 Jan 29. Neurochem Int. 2019. PMID: 30707915
490 results