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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
van der Linden L, Vives-Adrián L, Selisko B, Ferrer-Orta C, Liu X, Lanke K, Ulferts R, De Palma AM, Tanchis F, Goris N, Lefebvre D, De Clercq K, Leyssen P, Lacroix C, Pürstinger G, Coutard B, Canard B, Boehr DD, Arnold JJ, Cameron CE, Verdaguer N, Neyts J, van Kuppeveld FJ. van der Linden L, et al. Among authors: verdaguer n. PLoS Pathog. 2015 Mar 23;11(3):e1004733. doi: 10.1371/journal.ppat.1004733. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25799064 Free PMC article.
A comparison of viral RNA-dependent RNA polymerases.
Ferrer-Orta C, Arias A, Escarmís C, Verdaguer N. Ferrer-Orta C, et al. Among authors: verdaguer n. Curr Opin Struct Biol. 2006 Feb;16(1):27-34. doi: 10.1016/j.sbi.2005.12.002. Epub 2005 Dec 20. Curr Opin Struct Biol. 2006. PMID: 16364629 Review.
Sequential structures provide insights into the fidelity of RNA replication.
Ferrer-Orta C, Arias A, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. Ferrer-Orta C, et al. Among authors: verdaguer n. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9463-8. doi: 10.1073/pnas.0700518104. Epub 2007 May 21. Proc Natl Acad Sci U S A. 2007. PMID: 17517631 Free PMC article.
Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Garriga D, Navarro A, Querol-Audí J, Abaitua F, Rodríguez JF, Verdaguer N. Garriga D, et al. Among authors: verdaguer n. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20540-5. doi: 10.1073/pnas.0704447104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077388 Free PMC article.
110 results