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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
van der Linden L, Vives-Adrián L, Selisko B, Ferrer-Orta C, Liu X, Lanke K, Ulferts R, De Palma AM, Tanchis F, Goris N, Lefebvre D, De Clercq K, Leyssen P, Lacroix C, Pürstinger G, Coutard B, Canard B, Boehr DD, Arnold JJ, Cameron CE, Verdaguer N, Neyts J, van Kuppeveld FJ. van der Linden L, et al. Among authors: coutard b. PLoS Pathog. 2015 Mar 23;11(3):e1004733. doi: 10.1371/journal.ppat.1004733. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25799064 Free PMC article.
Preliminary crystallographic characterization of an RNA helicase from Kunjin virus.
Mastrangelo E, Bollati M, Milani M, Brisbarre N, de Lamballerie X, Coutard B, Canard B, Khromykh A, Bolognesi M. Mastrangelo E, et al. Among authors: coutard b. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt 9):876-9. doi: 10.1107/S1744309106028776. Epub 2006 Aug 11. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16946468 Free PMC article.
A second, non-canonical RNA-dependent RNA polymerase in SARS coronavirus.
Imbert I, Guillemot JC, Bourhis JM, Bussetta C, Coutard B, Egloff MP, Ferron F, Gorbalenya AE, Canard B. Imbert I, et al. Among authors: coutard b. EMBO J. 2006 Oct 18;25(20):4933-42. doi: 10.1038/sj.emboj.7601368. Epub 2006 Oct 5. EMBO J. 2006. PMID: 17024178 Free PMC article.
Purification and crystallization of Kokobera virus helicase.
De Colibus L, Speroni S, Coutard B, Forrester NL, Gould E, Canard B, Mattevi A. De Colibus L, et al. Among authors: coutard b. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):193-5. doi: 10.1107/S1744309107005283. Epub 2007 Feb 10. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17329812 Free PMC article.
Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase.
Jabafi I, Selisko B, Coutard B, De Palma AM, Neyts J, Egloff MP, Grisel S, Dalle K, Campanacci V, Spinelli S, Cambillau C, Canard B, Gruez A. Jabafi I, et al. Among authors: coutard b. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 1;63(Pt 6):495-8. doi: 10.1107/S1744309107020416. Epub 2007 May 12. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17554171 Free PMC article.
Structure and biochemical analysis of Kokobera virus helicase.
Speroni S, De Colibus L, Mastrangelo E, Gould E, Coutard B, Forrester NL, Blanc S, Canard B, Mattevi A. Speroni S, et al. Among authors: coutard b. Proteins. 2008 Feb 15;70(3):1120-3. doi: 10.1002/prot.21812. Proteins. 2008. PMID: 18004778 No abstract available.
The VIZIER project: preparedness against pathogenic RNA viruses.
Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B. Coutard B, et al. Antiviral Res. 2008 Apr;78(1):37-46. doi: 10.1016/j.antiviral.2007.10.013. Epub 2007 Nov 29. Antiviral Res. 2008. PMID: 18083241 Free PMC article.
134 results