Beedle AM - Search Results

1

Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics.

Hanold LE, Oruganty K, Ton NT, Beedle AM, Kannan N, Kennedy EJ. Hanold LE, et al. Among authors: beedle am. PLoS One. 2015 Mar 19;10(3):e0118796. doi: 10.1371/journal.pone.0118796. eCollection 2015. PLoS One. 2015. PMID: 25790232 Free PMC article.

2

Design of a selenylsulfide-bridged EGFR dimerization arm mimic.

Hanold LE, Watkins CP, Ton NT, Liaw P, Beedle AM, Kennedy EJ. Hanold LE, et al. Among authors: beedle am. Bioorg Med Chem. 2015 Jun 15;23(12):2761-6. doi: 10.1016/j.bmc.2015.03.040. Epub 2015 Mar 20. Bioorg Med Chem. 2015. PMID: 25840798 Free PMC article.

3

Conformationally constrained peptides target the allosteric kinase dimer interface and inhibit EGFR activation.

Fulton MD, Hanold LE, Ruan Z, Patel S, Beedle AM, Kannan N, Kennedy EJ. Fulton MD, et al. Among authors: beedle am. Bioorg Med Chem. 2018 Mar 15;26(6):1167-1173. doi: 10.1016/j.bmc.2017.08.051. Epub 2017 Sep 5. Bioorg Med Chem. 2018. PMID: 28911855 Free PMC article.

4

Lysophosphatidic Acid Mediates Activating Transcription Factor 3 Expression Which Is a Target for Post-Transcriptional Silencing by miR-30c-2-3p.

Nguyen HT, Jia W, Beedle AM, Kennedy EJ, Murph MM. Nguyen HT, et al. Among authors: beedle am. PLoS One. 2015 Sep 29;10(9):e0139489. doi: 10.1371/journal.pone.0139489. eCollection 2015. PLoS One. 2015. PMID: 26418018 Free PMC article.

5

Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue.

Fortunato MJ, Ball CE, Hollinger K, Patel NB, Modi JN, Rajasekaran V, Nonneman DJ, Ross JW, Kennedy EJ, Selsby JT, Beedle AM. Fortunato MJ, et al. Among authors: beedle am. PLoS One. 2014 May 13;9(5):e97567. doi: 10.1371/journal.pone.0097567. eCollection 2014. PLoS One. 2014. PMID: 24824861 Free PMC article.

6

Abnormal Skeletal Muscle Regeneration plus Mild Alterations in Mature Fiber Type Specification in Fktn-Deficient Dystroglycanopathy Muscular Dystrophy Mice.

Foltz SJ, Modi JN, Melick GA, Abousaud MI, Luan J, Fortunato MJ, Beedle AM. Foltz SJ, et al. Among authors: beedle am. PLoS One. 2016 Jan 11;11(1):e0147049. doi: 10.1371/journal.pone.0147049. eCollection 2016. PLoS One. 2016. PMID: 26751696 Free PMC article.

7

Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy.

Foltz SJ, Luan J, Call JA, Patel A, Peissig KB, Fortunato MJ, Beedle AM. Foltz SJ, et al. Among authors: beedle am. Skelet Muscle. 2016 Jun 2;6:20. doi: 10.1186/s13395-016-0091-9. eCollection 2016. Skelet Muscle. 2016. PMID: 27257474 Free PMC article.

8

Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model.

Altman MK, Nguyen DT, Patel SB, Fambrough JM, Beedle AM, Hardman WJ, Murph MM. Altman MK, et al. Among authors: beedle am. Biochem Res Int. 2012;2012:518437. doi: 10.1155/2012/518437. Epub 2012 Jun 25. Biochem Res Int. 2012. PMID: 22792465 Free PMC article.

9

Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy.

Beedle AM, Turner AJ, Saito Y, Lueck JD, Foltz SJ, Fortunato MJ, Nienaber PM, Campbell KP. Beedle AM, et al. J Clin Invest. 2012 Sep;122(9):3330-42. doi: 10.1172/JCI63004. Epub 2012 Aug 27. J Clin Invest. 2012. PMID: 22922256 Free PMC article.

10

Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.

Altman MK, Alshamrani AA, Jia W, Nguyen HT, Fambrough JM, Tran SK, Patel MB, Hoseinzadeh P, Beedle AM, Murph MM. Altman MK, et al. Among authors: beedle am. Cancer Lett. 2015 Dec 1;369(1):175-83. doi: 10.1016/j.canlet.2015.08.012. Epub 2015 Aug 28. Cancer Lett. 2015. PMID: 26319900 Free PMC article.

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