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SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres.
Gauchier M, Kan S, Barral A, Sauzet S, Agirre E, Bonnell E, Saksouk N, Barth TK, Ide S, Urbach S, Wellinger RJ, Luco RF, Imhof A, Déjardin J. Gauchier M, et al. Among authors: saksouk n. Sci Adv. 2019 May 8;5(5):eaav3673. doi: 10.1126/sciadv.aav3673. eCollection 2019 May. Sci Adv. 2019. PMID: 31086817 Free PMC article.
Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.
van Mierlo G, Dirks RAM, De Clerck L, Brinkman AB, Huth M, Kloet SL, Saksouk N, Kroeze LI, Willems S, Farlik M, Bock C, Jansen JH, Deforce D, Vermeulen M, Déjardin J, Dhaenens M, Marks H. van Mierlo G, et al. Among authors: saksouk n. Cell Stem Cell. 2019 Jan 3;24(1):123-137.e8. doi: 10.1016/j.stem.2018.10.017. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472157 Free article.
Histone H3 tail clipping regulates gene expression.
Santos-Rosa H, Kirmizis A, Nelson C, Bartke T, Saksouk N, Cote J, Kouzarides T. Santos-Rosa H, et al. Among authors: saksouk n. Nat Struct Mol Biol. 2009 Jan;16(1):17-22. doi: 10.1038/nsmb.1534. Epub 2008 Dec 14. Nat Struct Mol Biol. 2009. PMID: 19079264 Free PMC article.
The mouse HP1 proteins are essential for preventing liver tumorigenesis.
Saksouk N, Hajdari S, Perez Y, Pratlong M, Barrachina C, Graber C, Grégoire D, Zavoriti A, Sarrazin A, Pirot N, Noël JY, Khellaf L, Fabbrizio E, Julien E, Cammas FM. Saksouk N, et al. Oncogene. 2020 Mar;39(13):2676-2691. doi: 10.1038/s41388-020-1177-8. Epub 2020 Feb 4. Oncogene. 2020. PMID: 32020053
23 results