Callahan B - Search Results

1

Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activation.

Xie J, Owen T, Xia K, Singh AV, Tou E, Li L, Arduini B, Li H, Wan LQ, Callahan B, Wang C. Xie J, et al. Among authors: callahan b. J Biol Chem. 2015 May 1;290(18):11591-600. doi: 10.1074/jbc.M114.623264. Epub 2015 Mar 18. J Biol Chem. 2015. PMID: 25787080 Free PMC article.

2

¹H, ¹³C and ¹⁵N NMR assignments of a Drosophila Hedgehog autoprocessing domain.

Xie J, Du Z, Callahan B, Belfort M, Wang C. Xie J, et al. Among authors: callahan b. Biomol NMR Assign. 2014 Oct;8(2):279-81. doi: 10.1007/s12104-013-9500-8. Epub 2013 Jun 14. Biomol NMR Assign. 2014. PMID: 23765287 Free PMC article.

3

A Single Aspartate Coordinates Two Catalytic Steps in Hedgehog Autoprocessing.

Xie J, Owen T, Xia K, Callahan B, Wang C. Xie J, et al. Among authors: callahan b. J Am Chem Soc. 2016 Aug 31;138(34):10806-9. doi: 10.1021/jacs.6b06928. Epub 2016 Aug 19. J Am Chem Soc. 2016. PMID: 27529645 Free PMC article.

4

Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing.

Zhang X, Xu Z, Moumin DS, Ciulla DA, Owen TS, Mancusi RA, Giner JL, Wang C, Callahan BP. Zhang X, et al. Bioconjug Chem. 2019 Nov 20;30(11):2799-2804. doi: 10.1021/acs.bioconjchem.9b00550. Epub 2019 Oct 10. Bioconjug Chem. 2019. PMID: 31600061 Free PMC article.

5

Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.

Owen TS, Ngoje G, Lageman TJ, Bordeau BM, Belfort M, Callahan BP. Owen TS, et al. Anal Biochem. 2015 Nov 1;488:1-5. doi: 10.1016/j.ab.2015.06.021. Epub 2015 Jun 18. Anal Biochem. 2015. PMID: 26095399 Free PMC article.

6

General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing.

Zhao J, Ciulla DA, Xie J, Wagner AG, Castillo DA, Zwarycz AS, Lin Z, Beadle S, Giner JL, Li Z, Li H, Banavali N, Callahan BP, Wang C. Zhao J, et al. J Am Chem Soc. 2019 Nov 20;141(46):18380-18384. doi: 10.1021/jacs.9b08914. Epub 2019 Nov 7. J Am Chem Soc. 2019. PMID: 31682419 Free PMC article.

7

Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis.

Smith CJ, Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Giner JL, Xie J, Covey DF, Wang C, Callahan BP. Smith CJ, et al. Biochemistry. 2020 Feb 18;59(6):736-741. doi: 10.1021/acs.biochem.0c00013. Epub 2020 Feb 4. Biochemistry. 2020. PMID: 32013401 Free PMC article.

8

Active site targeting of hedgehog precursor protein with phenylarsine oxide.

Owen TS, Xie XJ, Laraway B, Ngoje G, Wang C, Callahan BP. Owen TS, et al. Among authors: callahan bp. Chembiochem. 2015 Jan 2;16(1):55-8. doi: 10.1002/cbic.201402421. Epub 2014 Nov 21. Chembiochem. 2015. PMID: 25418613 Free PMC article.

9

Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling.

Callahan BP, Wang C. Callahan BP, et al. Cancers (Basel). 2015 Oct 14;7(4):2037-53. doi: 10.3390/cancers7040875. Cancers (Basel). 2015. PMID: 26473928 Free PMC article. Review.

10

Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "Irreversibility Rule" for Protein Autoprocessing Inhibition.

Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Kandel N, Giner JL, Covey DF, Wang C, Callahan BP. Wagner AG, et al. Biochemistry. 2022 Jun 7;61(11):1022-1028. doi: 10.1021/acs.biochem.1c00697. Epub 2021 Dec 23. Biochemistry. 2022. PMID: 34941260 Free PMC article.

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