Fermeglia M - Search Results

1

Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3).

Brambilla L, Genini D, Laurini E, Merulla J, Perez L, Fermeglia M, Carbone GM, Pricl S, Catapano CV. Brambilla L, et al. Among authors: fermeglia m. Mol Oncol. 2015 Jun;9(6):1194-206. doi: 10.1016/j.molonc.2015.02.012. Epub 2015 Mar 5. Mol Oncol. 2015. PMID: 25777967 Free PMC article.

2

Through the open door: Preferential binding of dasatinib to the active form of BCR-ABL unveiled by in silico experiments.

Laurini E, Posocco P, Fermeglia M, Gibbons DL, Quintás-Cardama A, Pricl S. Laurini E, et al. Among authors: fermeglia m. Mol Oncol. 2013 Oct;7(5):968-75. doi: 10.1016/j.molonc.2013.06.001. Epub 2013 Jun 15. Mol Oncol. 2013. PMID: 23816609 Free PMC article.

3

Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma.

Pricl S, Cortelazzi B, Dal Col V, Marson D, Laurini E, Fermeglia M, Licitra L, Pilotti S, Bossi P, Perrone F. Pricl S, et al. Among authors: fermeglia m. Mol Oncol. 2015 Feb;9(2):389-97. doi: 10.1016/j.molonc.2014.09.003. Epub 2014 Sep 26. Mol Oncol. 2015. PMID: 25306392 Free PMC article.

4

T315I-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: insights from a computational study.

Pricl S, Fermeglia M, Ferrone M, Tamborini E. Pricl S, et al. Among authors: fermeglia m. Mol Cancer Ther. 2005 Aug;4(8):1167-74. doi: 10.1158/1535-7163.MCT-05-0101. Mol Cancer Ther. 2005. PMID: 16093432

5

Antimycobacterial activity of new 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-one derivatives. Molecular modeling investigations.

Zampieri D, Mamolo MG, Laurini E, Fermeglia M, Posocco P, Pricl S, Banfi E, Scialino G, Vio L. Zampieri D, et al. Among authors: fermeglia m. Bioorg Med Chem. 2009 Jul 1;17(13):4693-707. doi: 10.1016/j.bmc.2009.04.055. Epub 2009 May 3. Bioorg Med Chem. 2009. PMID: 19467603

6

Another brick in the wall. Validation of the σ1 receptor 3D model by computer-assisted design, synthesis, and activity of new σ1 ligands.

Laurini E, Marson D, Dal Col V, Fermeglia M, Mamolo MG, Zampieri D, Vio L, Pricl S. Laurini E, et al. Among authors: fermeglia m. Mol Pharm. 2012 Nov 5;9(11):3107-26. doi: 10.1021/mp300233y. Epub 2012 Oct 12. Mol Pharm. 2012. PMID: 23020867

7

Impact of siRNA overhangs for dendrimer-mediated siRNA delivery and gene silencing.

Posocco P, Liu X, Laurini E, Marson D, Chen C, Liu C, Fermeglia M, Rocchi P, Pricl S, Peng L. Posocco P, et al. Among authors: fermeglia m. Mol Pharm. 2013 Aug 5;10(8):3262-73. doi: 10.1021/mp400329g. Epub 2013 Jul 25. Mol Pharm. 2013. PMID: 23841848

8

Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands.

Zampieri D, Laurini E, Vio L, Golob S, Fermeglia M, Pricl S, Mamolo MG. Zampieri D, et al. Among authors: fermeglia m. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1021-5. doi: 10.1016/j.bmcl.2014.01.032. Epub 2014 Jan 20. Bioorg Med Chem Lett. 2014. PMID: 24486131

9

Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands.

Zampieri D, Vio L, Fermeglia M, Pricl S, Wünsch B, Schepmann D, Romano M, Mamolo MG, Laurini E. Zampieri D, et al. Among authors: fermeglia m. Eur J Med Chem. 2016 Oct 4;121:712-726. doi: 10.1016/j.ejmech.2016.06.001. Epub 2016 Jun 3. Eur J Med Chem. 2016. PMID: 27366902 Free article.

10

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

Colombo C, Belfiore A, Paielli N, De Cecco L, Canevari S, Laurini E, Fermeglia M, Pricl S, Verderio P, Bottelli S, Fiore M, Stacchiotti S, Palassini E, Gronchi A, Pilotti S, Perrone F. Colombo C, et al. Among authors: fermeglia m. Mol Oncol. 2017 Nov;11(11):1495-1507. doi: 10.1002/1878-0261.12101. Epub 2017 Sep 29. Mol Oncol. 2017. PMID: 28627792 Free PMC article.

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