Masterson LR - Search Results

1

Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation.

Kim J, Masterson LR, Cembran A, Verardi R, Shi L, Gao J, Taylor SS, Veglia G. Kim J, et al. Among authors: masterson lr. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3716-21. doi: 10.1073/pnas.1502299112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775607 Free PMC article.

2

Allosteric cooperativity in protein kinase A.

Masterson LR, Mascioni A, Traaseth NJ, Taylor SS, Veglia G. Masterson LR, et al. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):506-11. doi: 10.1073/pnas.0709214104. Epub 2008 Jan 4. Proc Natl Acad Sci U S A. 2008. PMID: 18178622 Free PMC article.

3

Dynamics connect substrate recognition to catalysis in protein kinase A.

Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G. Masterson LR, et al. Nat Chem Biol. 2010 Nov;6(11):821-8. doi: 10.1038/nchembio.452. Epub 2010 Oct 3. Nat Chem Biol. 2010. PMID: 20890288 Free PMC article.

4

Lethal Arg9Cys phospholamban mutation hinders Ca2+-ATPase regulation and phosphorylation by protein kinase A.

Ha KN, Masterson LR, Hou Z, Verardi R, Walsh N, Veglia G, Robia SL. Ha KN, et al. Among authors: masterson lr. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2735-40. doi: 10.1073/pnas.1013987108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21282613 Free PMC article.

5

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy.

Masterson LR, Shi L, Metcalfe E, Gao J, Taylor SS, Veglia G. Masterson LR, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6969-74. doi: 10.1073/pnas.1102701108. Epub 2011 Apr 6. Proc Natl Acad Sci U S A. 2011. PMID: 21471451 Free PMC article.

6

cAMP-dependent protein kinase A selects the excited state of the membrane substrate phospholamban.

Masterson LR, Yu T, Shi L, Wang Y, Gustavsson M, Mueller MM, Veglia G. Masterson LR, et al. J Mol Biol. 2011 Sep 16;412(2):155-64. doi: 10.1016/j.jmb.2011.06.041. Epub 2011 Jul 2. J Mol Biol. 2011. PMID: 21741980 Free PMC article.

7

Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations.

Masterson LR, Cembran A, Shi L, Veglia G. Masterson LR, et al. Adv Protein Chem Struct Biol. 2012;87:363-89. doi: 10.1016/B978-0-12-398312-1.00012-3. Adv Protein Chem Struct Biol. 2012. PMID: 22607761 Free PMC article. Review.

8

Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations.

Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G. Cembran A, et al. Among authors: masterson lr. Biochemistry. 2012 Dec 21;51(51):10186-96. doi: 10.1021/bi301279f. Epub 2012 Dec 12. Biochemistry. 2012. PMID: 23205665 Free PMC article.

9

Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling.

Srivastava AK, McDonald LR, Cembran A, Kim J, Masterson LR, McClendon CL, Taylor SS, Veglia G. Srivastava AK, et al. Among authors: masterson lr. Structure. 2014 Dec 2;22(12):1735-1743. doi: 10.1016/j.str.2014.09.010. Epub 2014 Nov 6. Structure. 2014. PMID: 25458836 Free PMC article.

10

Structural and dynamic basis of phospholamban and sarcolipin inhibition of Ca(2+)-ATPase.

Traaseth NJ, Ha KN, Verardi R, Shi L, Buffy JJ, Masterson LR, Veglia G. Traaseth NJ, et al. Among authors: masterson lr. Biochemistry. 2008 Jan 8;47(1):3-13. doi: 10.1021/bi701668v. Epub 2007 Dec 15. Biochemistry. 2008. PMID: 18081313 Free PMC article. Review.

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