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TGF-β1 pathway as a new target for neuroprotection in Alzheimer's disease.
Caraci F, Battaglia G, Bruno V, Bosco P, Carbonaro V, Giuffrida ML, Drago F, Sortino MA, Nicoletti F, Copani A. Caraci F, et al. CNS Neurosci Ther. 2011 Aug;17(4):237-49. doi: 10.1111/j.1755-5949.2009.00115.x. Epub 2009 Nov 19. CNS Neurosci Ther. 2011. PMID: 19925479 Free PMC article. Review.
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective.
Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F. Caraci F, et al. Mol Pharmacol. 2011 Mar;79(3):618-26. doi: 10.1124/mol.110.067488. Epub 2010 Dec 15. Mol Pharmacol. 2011. PMID: 21159998
The use of antidepressant drugs and the lifetime prevalence of major depressive disorders in Italy.
Carta MG, Aguglia E, Bocchetta A, Balestrieri M, Caraci F, Casacchia M, Dell'osso L, Sciascio GD, Drago F, Faravelli C, Lecca ME, Moro MF, Morosini PL, Nardini M, Palumbo G, Hardoy MC. Carta MG, et al. Among authors: caraci f. Clin Pract Epidemiol Ment Health. 2010 Aug 27;6:94-100. doi: 10.2174/1745017901006010094. Clin Pract Epidemiol Ment Health. 2010. PMID: 21253459 Free PMC article.
The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression.
Caraci F, Bosco P, Signorelli M, Spada RS, Cosentino FI, Toscano G, Bonforte C, Muratore S, Prestianni G, Panerai S, Giambirtone MC, Gulotta E, Romano C, Salluzzo MG, Nicoletti F, Copani A, Drago F, Aguglia E, Ferri R. Caraci F, et al. Eur Neuropsychopharmacol. 2012 Apr;22(4):281-9. doi: 10.1016/j.euroneuro.2011.08.006. Epub 2011 Sep 15. Eur Neuropsychopharmacol. 2012. PMID: 21924590
237 results