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Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model.
Chen Z, Earl P, Americo J, Damon I, Smith SK, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Gorshkova I, Schuck P, Satterfield W, Moss B, Purcell R. Chen Z, et al. Among authors: purcell r. J Virol. 2007 Sep;81(17):8989-95. doi: 10.1128/JVI.00906-07. Epub 2007 Jun 20. J Virol. 2007. PMID: 17581986 Free PMC article.
Monoclonal antibody therapies against anthrax.
Chen Z, Moayeri M, Purcell R. Chen Z, et al. Among authors: purcell r. Toxins (Basel). 2011 Aug;3(8):1004-19. doi: 10.3390/toxins3081004. Epub 2011 Aug 15. Toxins (Basel). 2011. PMID: 22069754 Free PMC article. Review.
Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice.
Altaweel L, Chen Z, Moayeri M, Cui X, Li Y, Su J, Fitz Y, Johnson S, Leppla SH, Purcell R, Eichacker PQ. Altaweel L, et al. Among authors: purcell r. Crit Care Med. 2011 Jun;39(6):1439-47. doi: 10.1097/CCM.0b013e3182120691. Crit Care Med. 2011. PMID: 21336113 Free PMC article.
920 results