Sola I - Search Results

1

Multigram synthesis and in vivo efficacy studies of a novel multitarget anti-Alzheimer's compound.

Sola I, Viayna E, Gómez T, Galdeano C, Cassina M, Camps P, Romeo M, Diomede L, Salmona M, Franco P, Schaeffer M, Colantuono D, Robin D, Brunner D, Taub N, Hutter-Paier B, Muñoz-Torrero D. Sola I, et al. Molecules. 2015 Mar 10;20(3):4492-515. doi: 10.3390/molecules20034492. Molecules. 2015. PMID: 25764491 Free PMC article.

2

Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases.

Galdeano C, Viayna E, Sola I, Formosa X, Camps P, Badia A, Clos MV, Relat J, Ratia M, Bartolini M, Mancini F, Andrisano V, Salmona M, Minguillón C, González-Muñoz GC, Rodríguez-Franco MI, Bidon-Chanal A, Luque FJ, Muñoz-Torrero D. Galdeano C, et al. Among authors: sola i. J Med Chem. 2012 Jan 26;55(2):661-9. doi: 10.1021/jm200840c. Epub 2012 Jan 10. J Med Chem. 2012. PMID: 22185619

3

Thioflavin-S staining of bacterial inclusion bodies for the fast, simple, and inexpensive screening of amyloid aggregation inhibitors.

Pouplana S, Espargaro A, Galdeano C, Viayna E, Sola I, Ventura S, Muñoz-Torrero D, Sabate R. Pouplana S, et al. Among authors: sola i. Curr Med Chem. 2014;21(9):1152-9. doi: 10.2174/09298673113206660256. Curr Med Chem. 2014. PMID: 24059241 Free article.

4

Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents.

Muñoz-Torrero D, Pera M, Relat J, Ratia M, Galdeano C, Viayna E, Sola I, Formosa X, Camps P, Badia A, Clos MV. Muñoz-Torrero D, et al. Among authors: sola i. Neurodegener Dis. 2012;10(1-4):96-9. doi: 10.1159/000333225. Epub 2012 Jan 6. Neurodegener Dis. 2012. PMID: 22236498

5

Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents.

Viayna E, Sola I, Bartolini M, De Simone A, Tapia-Rojas C, Serrano FG, Sabaté R, Juárez-Jiménez J, Pérez B, Luque FJ, Andrisano V, Clos MV, Inestrosa NC, Muñoz-Torrero D. Viayna E, et al. Among authors: sola i. J Med Chem. 2014 Mar 27;57(6):2549-67. doi: 10.1021/jm401824w. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24568372 Free article.

6

Human disease and drug pharmacology, complex as real life.

Viayna E, Sola I, Di Pietro O, Muñoz-Torrero D. Viayna E, et al. Among authors: sola i. Curr Med Chem. 2013;20(13):1623-34. doi: 10.2174/0929867311320130002. Curr Med Chem. 2013. PMID: 23410162 Free article. Review.

7

Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity.

Sola I, Castellà S, Viayna E, Galdeano C, Taylor MC, Gbedema SY, Pérez B, Clos MV, Jones DC, Fairlamb AH, Wright CW, Kelly JM, Muñoz-Torrero D. Sola I, et al. Bioorg Med Chem. 2015 Aug 15;23(16):5156-67. doi: 10.1016/j.bmc.2015.01.031. Epub 2015 Jan 24. Bioorg Med Chem. 2015. PMID: 25678015

8

Novel Levetiracetam Derivatives That Are Effective against the Alzheimer-like Phenotype in Mice: Synthesis, in Vitro, ex Vivo, and in Vivo Efficacy Studies.

Sola I, Aso E, Frattini D, López-González I, Espargaró A, Sabaté R, Di Pietro O, Luque FJ, Clos MV, Ferrer I, Muñoz-Torrero D. Sola I, et al. J Med Chem. 2015 Aug 13;58(15):6018-32. doi: 10.1021/acs.jmedchem.5b00624. Epub 2015 Jul 27. J Med Chem. 2015. PMID: 26181606

9

Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.

Sola I, Artigas A, Taylor MC, Pérez-Areales FJ, Viayna E, Clos MV, Pérez B, Wright CW, Kelly JM, Muñoz-Torrero D. Sola I, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5162-5171. doi: 10.1016/j.bmc.2016.08.036. Epub 2016 Aug 22. Bioorg Med Chem. 2016. PMID: 27591008 Free PMC article.

10

Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.

Di Pietro O, Vicente-García E, Taylor MC, Berenguer D, Viayna E, Lanzoni A, Sola I, Sayago H, Riera C, Fisa R, Clos MV, Pérez B, Kelly JM, Lavilla R, Muñoz-Torrero D. Di Pietro O, et al. Among authors: sola i. Eur J Med Chem. 2015 Nov 13;105:120-37. doi: 10.1016/j.ejmech.2015.10.007. Epub 2015 Oct 19. Eur J Med Chem. 2015. PMID: 26479031 Free PMC article.

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