Leach MO - Search Results

1

Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours.

Beloueche-Babari M, Box C, Arunan V, Parkes HG, Valenti M, De Haven Brandon A, Jackson LE, Eccles SA, Leach MO. Beloueche-Babari M, et al. Among authors: leach mo. Br J Cancer. 2015 Mar 31;112(7):1206-14. doi: 10.1038/bjc.2015.86. Br J Cancer. 2015. PMID: 25742484 Free PMC article.

2

Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells.

Ronen SM, Jackson LE, Beloueche M, Leach MO. Ronen SM, et al. Among authors: leach mo. Br J Cancer. 2001 Mar 2;84(5):691-6. doi: 10.1054/bjoc.2000.1663. Br J Cancer. 2001. PMID: 11237392 Free PMC article.

3

Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy.

Beloueche-Babari M, Chung YL, Al-Saffar NM, Falck-Miniotis M, Leach MO. Beloueche-Babari M, et al. Among authors: leach mo. Br J Cancer. 2010 Jan 5;102(1):1-7. doi: 10.1038/sj.bjc.6605457. Epub 2009 Nov 24. Br J Cancer. 2010. PMID: 19935796 Free PMC article. Review.

4

Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI.

Beloueche-Babari M, Jamin Y, Arunan V, Walker-Samuel S, Revill M, Smith PD, Halliday J, Waterton JC, Barjat H, Workman P, Leach MO, Robinson SP. Beloueche-Babari M, et al. Among authors: leach mo. Br J Cancer. 2013 Sep 17;109(6):1562-9. doi: 10.1038/bjc.2013.456. Epub 2013 Aug 13. Br J Cancer. 2013. PMID: 23942066 Free PMC article.

5

Dichloroacetate induces autophagy in colorectal cancer cells and tumours.

Lin G, Hill DK, Andrejeva G, Boult JK, Troy H, Fong AC, Orton MR, Panek R, Parkes HG, Jafar M, Koh DM, Robinson SP, Judson IR, Griffiths JR, Leach MO, Eykyn TR, Chung YL. Lin G, et al. Among authors: leach mo. Br J Cancer. 2014 Jul 15;111(2):375-85. doi: 10.1038/bjc.2014.281. Epub 2014 Jun 3. Br J Cancer. 2014. PMID: 24892448 Free PMC article.

6

The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate.

Smith TA, Eccles S, Ormerod MG, Tombs AJ, Titley JC, Leach MO. Smith TA, et al. Among authors: leach mo. Br J Cancer. 1991 Nov;64(5):821-6. doi: 10.1038/bjc.1991.407. Br J Cancer. 1991. PMID: 1931601 Free PMC article.

7

Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells.

Al-Saffar NM, Titley JC, Robertson D, Clarke PA, Jackson LE, Leach MO, Ronen SM. Al-Saffar NM, et al. Among authors: leach mo. Br J Cancer. 2002 Mar 18;86(6):963-70. doi: 10.1038/sj.bjc.6600188. Br J Cancer. 2002. PMID: 11953830 Free PMC article.

8

The effect of oestrogen ablation on the phospholipid metabolite content of primary and transplanted rat mammary tumours.

Smith TA, Baluch S, Titley JC, Ormerod MG, Eccles S, Tombs AJ, Leach MO, Griffiths JR, McCready VR. Smith TA, et al. Among authors: leach mo. NMR Biomed. 1993 May-Jun;6(3):209-14. doi: 10.1002/nbm.1940060307. NMR Biomed. 1993. PMID: 8347455

9

Treatment of SW620 cells with Tomudex and oxaliplatin induces changes in 2-deoxy-D-glucose incorporation associated with modifications in glucose transport.

Smith TA, Maisey NR, Titley JC, Jackson LE, Leach MO, Ronen SM. Smith TA, et al. Among authors: leach mo. J Nucl Med. 2000 Oct;41(10):1753-9. J Nucl Med. 2000. PMID: 11038008 Free article.

10

Phosphocholine and choline content of rat sarcoma cells grown in the presence and absence of serum.

Smith TA, Eccles S, Box G, Titley JC, Leach MO, McCready VR. Smith TA, et al. Among authors: leach mo. Anticancer Res. 1996 May-Jun;16(3B):1389-92. Anticancer Res. 1996. PMID: 8694506

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