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NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases.
Sehnert B, Burkhardt H, Wessels JT, Schröder A, May MJ, Vestweber D, Zwerina J, Warnatz K, Nimmerjahn F, Schett G, Dübel S, Voll RE. Sehnert B, et al. Among authors: zwerina j. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16556-61. doi: 10.1073/pnas.1218219110. Epub 2013 Sep 23. Proc Natl Acad Sci U S A. 2013. PMID: 24062461 Free PMC article.
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G. Krönke G, et al. Among authors: zwerina j. J Immunol. 2009 Sep 1;183(5):3383-9. doi: 10.4049/jimmunol.0900327. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675173 Free article.
Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis.
Ruiz-Heiland G, Horn A, Zerr P, Hofstetter W, Baum W, Stock M, Distler JH, Nimmerjahn F, Schett G, Zwerina J. Ruiz-Heiland G, et al. Among authors: zwerina j. Ann Rheum Dis. 2012 Mar;71(3):400-7. doi: 10.1136/ard.2010.148262. Epub 2012 Jan 10. Ann Rheum Dis. 2012. PMID: 22233602
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.
Uderhardt S, Diarra D, Katzenbeisser J, David JP, Zwerina J, Richards W, Kronke G, Schett G. Uderhardt S, et al. Among authors: zwerina j. Ann Rheum Dis. 2010 Mar;69(3):592-7. doi: 10.1136/ard.2008.102046. Epub 2009 Mar 19. Ann Rheum Dis. 2010. PMID: 19304568
217 results