Nimmerjahn F - Search Results

1

Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity.

Washburn N, Schwab I, Ortiz D, Bhatnagar N, Lansing JC, Medeiros A, Tyler S, Mekala D, Cochran E, Sarvaiya H, Garofalo K, Meccariello R, Meador JW 3rd, Rutitzky L, Schultes BC, Ling L, Avery W, Nimmerjahn F, Manning AM, Kaundinya GV, Bosques CJ. Washburn N, et al. Among authors: nimmerjahn f. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1297-306. doi: 10.1073/pnas.1422481112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733881 Free PMC article.

2

Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation.

Kaneko Y, Nimmerjahn F, Ravetch JV. Kaneko Y, et al. Among authors: nimmerjahn f. Science. 2006 Aug 4;313(5787):670-3. doi: 10.1126/science.1129594. Science. 2006. PMID: 16888140

3

Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.

Nimmerjahn F, Anthony RM, Ravetch JV. Nimmerjahn F, et al. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8433-7. doi: 10.1073/pnas.0702936104. Epub 2007 May 7. Proc Natl Acad Sci U S A. 2007. PMID: 17485663 Free PMC article.

4

Anti-inflammatory actions of intravenous immunoglobulin.

Nimmerjahn F, Ravetch JV. Nimmerjahn F, et al. Annu Rev Immunol. 2008;26:513-33. doi: 10.1146/annurev.immunol.26.021607.090232. Annu Rev Immunol. 2008. PMID: 18370923 Review.

5

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

Anthony RM, Nimmerjahn F, Ashline DJ, Reinhold VN, Paulson JC, Ravetch JV. Anthony RM, et al. Among authors: nimmerjahn f. Science. 2008 Apr 18;320(5874):373-6. doi: 10.1126/science.1154315. Science. 2008. PMID: 18420934 Free PMC article.

6

Mechanisms of action of intravenous immunoglobulins.

Baerenwaldt A, Biburger M, Nimmerjahn F. Baerenwaldt A, et al. Among authors: nimmerjahn f. Expert Rev Clin Immunol. 2010 May;6(3):425-34. doi: 10.1586/eci.10.9. Expert Rev Clin Immunol. 2010. PMID: 20441428 Review.

7

FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo.

Nimmerjahn F, Lux A, Albert H, Woigk M, Lehmann C, Dudziak D, Smith P, Ravetch JV. Nimmerjahn F, et al. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19396-401. doi: 10.1073/pnas.1014515107. Epub 2010 Oct 25. Proc Natl Acad Sci U S A. 2010. PMID: 20974962 Free PMC article.

8

Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo.

Baerenwaldt A, Lux A, Danzer H, Spriewald BM, Ullrich E, Heidkamp G, Dudziak D, Nimmerjahn F. Baerenwaldt A, et al. Among authors: nimmerjahn f. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18772-7. doi: 10.1073/pnas.1111810108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065769 Free PMC article.

9

Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo.

Biburger M, Aschermann S, Schwab I, Lux A, Albert H, Danzer H, Woigk M, Dudziak D, Nimmerjahn F. Biburger M, et al. Among authors: nimmerjahn f. Immunity. 2011 Dec 23;35(6):932-44. doi: 10.1016/j.immuni.2011.11.009. Epub 2011 Dec 8. Immunity. 2011. PMID: 22169040 Free article.

10

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

Schwab I, Biburger M, Krönke G, Schett G, Nimmerjahn F. Schwab I, et al. Among authors: nimmerjahn f. Eur J Immunol. 2012 Apr;42(4):826-30. doi: 10.1002/eji.201142260. Eur J Immunol. 2012. PMID: 22278120 Free article.

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