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A regulatory mechanism involving TBP-1/Tat-Binding Protein 1 and Akt/PKB in the control of cell proliferation.
Sepe M, Festa L, Tolino F, Bellucci L, Sisto L, Alfano D, Ragno P, Calabrò V, de Franciscis V, La Mantia G, Pollice A. Sepe M, et al. PLoS One. 2011;6(10):e22800. doi: 10.1371/journal.pone.0022800. Epub 2011 Oct 4. PLoS One. 2011. Retraction in: PLoS One. 2019 Sep 4;14(9):e0222287. doi: 10.1371/journal.pone.0222287 PMID: 21991300 Free PMC article. Retracted.
Control of PKA stability and signalling by the RING ligase praja2.
Lignitto L, Carlucci A, Sepe M, Stefan E, Cuomo O, Nisticò R, Scorziello A, Savoia C, Garbi C, Annunziato L, Feliciello A. Lignitto L, et al. Among authors: sepe m. Nat Cell Biol. 2011 Apr;13(4):412-22. doi: 10.1038/ncb2209. Epub 2011 Mar 20. Nat Cell Biol. 2011. PMID: 21423175
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.
Lignitto L, Arcella A, Sepe M, Rinaldi L, Delle Donne R, Gallo A, Stefan E, Bachmann VA, Oliva MA, Tiziana Storlazzi C, L'Abbate A, Brunetti A, Gargiulo S, Gramanzini M, Insabato L, Garbi C, Gottesman ME, Feliciello A. Lignitto L, et al. Among authors: sepe m. Nat Commun. 2013;4:1822. doi: 10.1038/ncomms2791. Nat Commun. 2013. PMID: 23652010 Free PMC article.
praja2 regulates KSR1 stability and mitogenic signaling.
Rinaldi L, Delle Donne R, Sepe M, Porpora M, Garbi C, Chiuso F, Gallo A, Parisi S, Russo L, Bachmann V, Huber RG, Stefan E, Russo T, Feliciello A. Rinaldi L, et al. Among authors: sepe m. Cell Death Dis. 2016 May 19;7(5):e2230. doi: 10.1038/cddis.2016.109. Cell Death Dis. 2016. PMID: 27195677 Free PMC article.
Proteolytic control of neurite outgrowth inhibitor NOGO-A by the cAMP/PKA pathway.
Sepe M, Lignitto L, Porpora M, Delle Donne R, Rinaldi L, Belgianni G, Colucci G, Cuomo O, Viggiano D, Scorziello A, Garbi C, Annunziato L, Feliciello A. Sepe M, et al. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15729-34. doi: 10.1073/pnas.1410274111. Epub 2014 Oct 20. Proc Natl Acad Sci U S A. 2014. PMID: 25331889 Free PMC article.
A dynamic interface between ubiquitylation and cAMP signaling.
Rinaldi L, Sepe M, Donne RD, Feliciello A. Rinaldi L, et al. Among authors: sepe m. Front Pharmacol. 2015 Sep 4;6:177. doi: 10.3389/fphar.2015.00177. eCollection 2015. Front Pharmacol. 2015. PMID: 26388770 Free PMC article. Review.
Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis.
Schiattarella GG, Cattaneo F, Pironti G, Magliulo F, Carotenuto G, Pirozzi M, Polishchuk R, Borzacchiello D, Paolillo R, Oliveti M, Boccella N, Avvedimento M, Sepe M, Lombardi A, Busiello RA, Trimarco B, Esposito G, Feliciello A, Perrino C. Schiattarella GG, et al. Among authors: sepe m. PLoS One. 2016 May 2;11(5):e0154076. doi: 10.1371/journal.pone.0154076. eCollection 2016. PLoS One. 2016. PMID: 27136357 Free PMC article.
Mitochondrial AKAP1 supports mTOR pathway and tumor growth.
Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A. Rinaldi L, et al. Among authors: sepe m. Cell Death Dis. 2017 Jun 1;8(6):e2842. doi: 10.1038/cddis.2017.241. Cell Death Dis. 2017. PMID: 28569781 Free PMC article.
38 results