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FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.
Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, Hernando E, Aifantis I. Kourtis N, et al. Among authors: hernando e. Nat Cell Biol. 2015 Mar;17(3):322-332. doi: 10.1038/ncb3121. Nat Cell Biol. 2015. PMID: 25720964 Free PMC article.
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Guardavaccaro D, et al. Among authors: hernando e. Nature. 2008 Mar 20;452(7185):365-9. doi: 10.1038/nature06641. Nature. 2008. PMID: 18354482 Free PMC article.
Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor.
Segura MF, Hanniford D, Menendez S, Reavie L, Zou X, Alvarez-Diaz S, Zakrzewski J, Blochin E, Rose A, Bogunovic D, Polsky D, Wei J, Lee P, Belitskaya-Levy I, Bhardwaj N, Osman I, Hernando E. Segura MF, et al. Among authors: hernando e. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1814-9. doi: 10.1073/pnas.0808263106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188590 Free PMC article.
Melanoma MicroRNA signature predicts post-recurrence survival.
Segura MF, Belitskaya-Lévy I, Rose AE, Zakrzewski J, Gaziel A, Hanniford D, Darvishian F, Berman RS, Shapiro RL, Pavlick AC, Osman I, Hernando E. Segura MF, et al. Among authors: hernando e. Clin Cancer Res. 2010 Mar 1;16(5):1577-86. doi: 10.1158/1078-0432.CCR-09-2721. Epub 2010 Feb 23. Clin Cancer Res. 2010. PMID: 20179230 Free PMC article.
Clinical relevance of SKP2 alterations in metastatic melanoma.
Rose AE, Wang G, Hanniford D, Monni S, Tu T, Shapiro RL, Berman RS, Pavlick AC, Pagano M, Darvishian F, Mazumdar M, Hernando E, Osman I. Rose AE, et al. Among authors: hernando e. Pigment Cell Melanoma Res. 2011 Feb;24(1):197-206. doi: 10.1111/j.1755-148X.2010.00784.x. Epub 2010 Oct 21. Pigment Cell Melanoma Res. 2011. PMID: 20883453 Free PMC article.
Efficient in vivo microRNA targeting of liver metastasis.
Huynh C, Segura MF, Gaziel-Sovran A, Menendez S, Darvishian F, Chiriboga L, Levin B, Meruelo D, Osman I, Zavadil J, Marcusson EG, Hernando E. Huynh C, et al. Among authors: hernando e. Oncogene. 2011 Mar 24;30(12):1481-8. doi: 10.1038/onc.2010.523. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102518
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.
Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. Kapoor A, et al. Among authors: hernando e. Nature. 2010 Dec 23;468(7327):1105-9. doi: 10.1038/nature09590. Nature. 2010. PMID: 21179167 Free PMC article.
Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.
Rose AE, Poliseno L, Wang J, Clark M, Pearlman A, Wang G, Vega Y Saenz de Miera EC, Medicherla R, Christos PJ, Shapiro R, Pavlick A, Darvishian F, Zavadil J, Polsky D, Hernando E, Ostrer H, Osman I. Rose AE, et al. Among authors: hernando e. Cancer Res. 2011 Apr 1;71(7):2561-71. doi: 10.1158/0008-5472.CAN-10-2958. Epub 2011 Feb 22. Cancer Res. 2011. PMID: 21343389 Free PMC article.
Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival.
Zakrzewski J, Geraghty LN, Rose AE, Christos PJ, Mazumdar M, Polsky D, Shapiro R, Berman R, Darvishian F, Hernando E, Pavlick A, Osman I. Zakrzewski J, et al. Among authors: hernando e. Cancer. 2011 Apr 15;117(8):1711-20. doi: 10.1002/cncr.25643. Epub 2010 Nov 8. Cancer. 2011. PMID: 21472718 Free PMC article.
169 results