Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases.
Mallart S, Ingenito R, Magotti P, Bresciani A, Di Marco A, Esposito S, Monteagudo E, Caretti F, Orsatti L, Santoprete A, Roversi D, Tucci F, Veneziano M, Brasseur D, Chénedé X, Corbier A, Gauzy-Lazo L, Gervat V, Marguet F, Minoletti C, Pasquier O, Poirier B, Azam A, Maillère B, Bianchi E, Janiak P, Duclos O, Illiano S.
Mallart S, et al. Among authors: bianchi e.
J Med Chem. 2025 Jan 31. doi: 10.1021/acs.jmedchem.4c03085. Online ahead of print.
J Med Chem. 2025.
PMID: 39888342