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Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer.
Neeb A, Figueiredo I, Bogdan D, Cato L, Stober J, Jiménez-Vacas JM, Gourain V, Lee II, Seeger R, Muhle-Goll C, Gurel B, Welti J, Nava Rodrigues D, Rekowski J, Qiu X, Jiang Y, Di Micco P, Mateos B, Bielskutė S, Riisnaes R, Ferreira A, Miranda S, Crespo M, Buroni L, Ning J, Carreira S, Bräse S, Jung N, Gräßle S, Swain A, Salvatella X, Plymate SR, Al-Lazikani B, Long HW, Yuan W, Brown M, Cato ACB, de Bono JS, Sharp A. Neeb A, et al. Among authors: al lazikani b. Mol Cancer Ther. 2024 Jun 4;23(6):791-808. doi: 10.1158/1535-7163.MCT-23-0354. Mol Cancer Ther. 2024. PMID: 38412481 Free PMC article.
canSAR 2024-an update to the public drug discovery knowledgebase.
Gingrich PW, Chitsazi R, Biswas A, Jiang C, Zhao L, Tym JE, Brammer KM, Li J, Shu Z, Maxwell DS, Tacy JA, Mica IL, Darkoh M, di Micco P, Russell KP, Workman P, Al-Lazikani B. Gingrich PW, et al. Among authors: al lazikani b. Nucleic Acids Res. 2024 Nov 13:gkae1050. doi: 10.1093/nar/gkae1050. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39535036
Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
Drugging cancer genomes.
Workman P, Al-Lazikani B. Workman P, et al. Nat Rev Drug Discov. 2013 Dec;12(12):889-90. doi: 10.1038/nrd4184. Nat Rev Drug Discov. 2013. PMID: 24287764 No abstract available.
canSAR: updated cancer research and drug discovery knowledgebase.
Bulusu KC, Tym JE, Coker EA, Schierz AC, Al-Lazikani B. Bulusu KC, et al. Nucleic Acids Res. 2014 Jan;42(Database issue):D1040-7. doi: 10.1093/nar/gkt1182. Epub 2013 Dec 3. Nucleic Acids Res. 2014. PMID: 24304894 Free PMC article.
canSAR: an updated cancer research and drug discovery knowledgebase.
Tym JE, Mitsopoulos C, Coker EA, Razaz P, Schierz AC, Antolin AA, Al-Lazikani B. Tym JE, et al. Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673713 Free PMC article.
Distinctive Behaviors of Druggable Proteins in Cellular Networks.
Mitsopoulos C, Schierz AC, Workman P, Al-Lazikani B. Mitsopoulos C, et al. PLoS Comput Biol. 2015 Dec 23;11(12):e1004597. doi: 10.1371/journal.pcbi.1004597. eCollection 2015 Dec. PLoS Comput Biol. 2015. PMID: 26699810 Free PMC article.
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