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Page 1
Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists.
Austin RP, Bennion C, Bonnert RV, Cheema L, Cook AR, Cox RJ, Ebden MR, Gaw A, Grime K, Meghani P, Nicholls D, Phillips C, Smith N, Steele J, Stonehouse JP. Austin RP, et al. Among authors: cox rj. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1616-20. doi: 10.1016/j.bmcl.2015.01.067. Epub 2015 Feb 3. Bioorg Med Chem Lett. 2015. PMID: 25708618
Small Molecule CXCR3 Antagonists.
Andrews SP, Cox RJ. Andrews SP, et al. Among authors: cox rj. J Med Chem. 2016 Apr 14;59(7):2894-917. doi: 10.1021/acs.jmedchem.5b01337. Epub 2015 Nov 4. J Med Chem. 2016. PMID: 26535614 Review.
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors.
Pemberton N, Mogemark M, Arlbrandt S, Bold P, Cox RJ, Gardelli C, Holden NS, Karabelas K, Karlsson J, Lever S, Li X, Lindmark H, Norberg M, Perry MWD, Petersen J, Rodrigo Blomqvist S, Thomas M, Tyrchan C, Westin Eriksson A, Zlatoidsky P, Öster L. Pemberton N, et al. Among authors: cox rj. J Med Chem. 2018 Jun 28;61(12):5435-5441. doi: 10.1021/acs.jmedchem.8b00447. Epub 2018 Jun 18. J Med Chem. 2018. PMID: 29852070
The powerful symbiosis between synthetic and medicinal chemistry.
Schiesser S, Cox RJ, Czechtizky W. Schiesser S, et al. Among authors: cox rj. Future Med Chem. 2021 Jun;13(11):941-944. doi: 10.4155/fmc-2021-0062. Epub 2021 Apr 21. Future Med Chem. 2021. PMID: 33878945 Free article. No abstract available.
Advances in the design of new types of inhaled medicines.
Czechtizky W, Su W, Ripa L, Schiesser S, Höijer A, Cox RJ. Czechtizky W, et al. Among authors: cox rj. Prog Med Chem. 2022;61:93-162. doi: 10.1016/bs.pmch.2022.04.001. Epub 2022 Jun 2. Prog Med Chem. 2022. PMID: 35753716 Review.
A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis.
Dumont C, Sivars U, Andreasson T, Odqvist L, Mattsson J, DeMicco A, Pardali K, Johansson G, Yrlid L, Cox RJ, Seeliger F, Larsson M, Gehrmann U, Davis AM, Vaarala O. Dumont C, et al. Among authors: cox rj. PLoS One. 2020 Sep 1;15(9):e0222548. doi: 10.1371/journal.pone.0222548. eCollection 2020. PLoS One. 2020. PMID: 32870913 Free PMC article.
347 results