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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. Gardner MR, et al. Among authors: quinlan bd. Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. Nature. 2015. PMID: 25707797 Free PMC article.
Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2.
Mou H, Quinlan BD, Peng H, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, Voo ZX, Bailey CC, Alpert MD, Rader C, Choe H, Farzan M. Mou H, et al. Among authors: quinlan bd. bioRxiv [Preprint]. 2020 Jun 30:2020.06.29.178459. doi: 10.1101/2020.06.29.178459. bioRxiv. 2020. Update in: PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501 PMID: 32637954 Free PMC article. Updated. Preprint.
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. Xiao T, et al. Among authors: quinlan bd. Nat Struct Mol Biol. 2021 Feb;28(2):202-209. doi: 10.1038/s41594-020-00549-3. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432247 Free PMC article.
21 results