Lu M - Search Results

1

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

Li P, Oh DY, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM. Li P, et al. Among authors: lu m. Nat Med. 2015 Mar;21(3):239-247. doi: 10.1038/nm.3800. Epub 2015 Feb 23. Nat Med. 2015. PMID: 25706874 Free PMC article.

2

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.

Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. Yoshizaki T, et al. Among authors: lu m. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E419-28. doi: 10.1152/ajpendo.00417.2009. Epub 2009 Dec 8. Am J Physiol Endocrinol Metab. 2010. PMID: 19996381 Free PMC article.

3

Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones.

Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. Lu M, et al. Nat Med. 2011 May;17(5):618-22. doi: 10.1038/nm.2332. Epub 2011 May 1. Nat Med. 2011. PMID: 21532596 Free PMC article.

4

Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity.

Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM. Li P, et al. Among authors: lu m. Cell. 2011 Nov 11;147(4):815-26. doi: 10.1016/j.cell.2011.09.050. Cell. 2011. PMID: 22078880 Free PMC article.

5

G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.

Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. Osborn O, et al. Among authors: lu m. J Clin Invest. 2012 Jul;122(7):2444-53. doi: 10.1172/JCI61953. Epub 2012 Jun 1. J Clin Invest. 2012. PMID: 22653059 Free PMC article.

6

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase.

Talukdar S, Oh DY, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. Talukdar S, et al. Among authors: lu m. Nat Med. 2012 Sep;18(9):1407-12. doi: 10.1038/nm.2885. Nat Med. 2012. PMID: 22863787 Free PMC article.

7

Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues.

Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Lu M, et al. J Biol Chem. 2013 Apr 12;288(15):10722-35. doi: 10.1074/jbc.M112.443606. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457303 Free PMC article.

8

NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids.

Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. Li P, et al. Among authors: lu m. Cell. 2013 Sep 26;155(1):200-214. doi: 10.1016/j.cell.2013.08.054. Cell. 2013. PMID: 24074869 Free PMC article.

9

Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance.

Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AMF, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, Ying W, Osborn O, Wollam J, Brenner M, Olefsky JM. Li P, et al. Among authors: lu m. Cell. 2016 Nov 3;167(4):973-984.e12. doi: 10.1016/j.cell.2016.10.025. Cell. 2016. PMID: 27814523 Free PMC article.

10

A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats.

Lu M, Patsouris D, Li P, Flores-Riveros J, Frincke JM, Watkins S, Schenk S, Olefsky JM. Lu M, et al. Am J Physiol Endocrinol Metab. 2010 May;298(5):E1036-48. doi: 10.1152/ajpendo.00668.2009. Epub 2010 Feb 16. Am J Physiol Endocrinol Metab. 2010. PMID: 20159859 Free PMC article. Clinical Trial.

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