Srinivasan B - Search Results

1

Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function.

Skolnick J, Gao M, Roy A, Srinivasan B, Zhou H. Skolnick J, et al. Among authors: srinivasan b. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1163-70. doi: 10.1016/j.bmcl.2015.01.059. Epub 2015 Feb 3. Bioorg Med Chem Lett. 2015. PMID: 25690787 Free PMC article. Review.

2

Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders.

Srinivasan B, Zhou H, Kubanek J, Skolnick J. Srinivasan B, et al. J Cheminform. 2014 Apr 26;6:16. doi: 10.1186/1758-2946-6-16. eCollection 2014. J Cheminform. 2014. PMID: 24936211 Free PMC article.

3

Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors.

Srinivasan B, Skolnick J. Srinivasan B, et al. FEBS J. 2015 May;282(10):1922-38. doi: 10.1111/febs.13244. Epub 2015 Mar 6. FEBS J. 2015. PMID: 25703118 Free PMC article.

4

PoLi: A Virtual Screening Pipeline Based on Template Pocket and Ligand Similarity.

Roy A, Srinivasan B, Skolnick J. Roy A, et al. Among authors: srinivasan b. J Chem Inf Model. 2015 Aug 24;55(8):1757-70. doi: 10.1021/acs.jcim.5b00232. Epub 2015 Aug 12. J Chem Inf Model. 2015. PMID: 26225536 Free PMC article.

5

Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.

Srinivasan B, Tonddast-Navaei S, Skolnick J. Srinivasan B, et al. Eur J Med Chem. 2015 Oct 20;103:600-14. doi: 10.1016/j.ejmech.2015.08.021. Epub 2015 Sep 5. Eur J Med Chem. 2015. PMID: 26414808 Free PMC article.

6

Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities.

Nagamallu R, Srinivasan B, Ningappa MB, Kariyappa AK. Nagamallu R, et al. Among authors: srinivasan b. Bioorg Med Chem Lett. 2016 Jan 15;26(2):690-694. doi: 10.1016/j.bmcl.2015.11.038. Epub 2015 Nov 12. Bioorg Med Chem Lett. 2016. PMID: 26631319

7

Catalytic and substrate promiscuity: distinct multiple chemistries catalysed by the phosphatase domain of receptor protein tyrosine phosphatase.

Srinivasan B, Marks H, Mitra S, Smalley DM, Skolnick J. Srinivasan B, et al. Biochem J. 2016 Jul 15;473(14):2165-77. doi: 10.1042/BCJ20160289. Epub 2016 May 17. Biochem J. 2016. PMID: 27208174 Free PMC article.

8

Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies.

Raghavendra KR, Renuka N, Kameshwar VH, Srinivasan B, Ajay Kumar K, Shashikanth S. Raghavendra KR, et al. Among authors: srinivasan b. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3621-5. doi: 10.1016/j.bmcl.2016.06.005. Epub 2016 Jun 4. Bioorg Med Chem Lett. 2016. PMID: 27318538

9

Repurposing FDA-approved drugs for anti-aging therapies.

Snell TW, Johnston RK, Srinivasan B, Zhou H, Gao M, Skolnick J. Snell TW, et al. Among authors: srinivasan b. Biogerontology. 2016 Nov;17(5-6):907-920. doi: 10.1007/s10522-016-9660-x. Epub 2016 Aug 2. Biogerontology. 2016. PMID: 27484416 Free PMC article.

10

Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway.

Srinivasan B, Zhou H, Mitra S, Skolnick J. Srinivasan B, et al. Bioorg Med Chem. 2016 Oct 1;24(19):4750-4758. doi: 10.1016/j.bmc.2016.08.019. Epub 2016 Aug 13. Bioorg Med Chem. 2016. PMID: 27567076 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

551 results

Search Page

Filters