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WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.
Boulter L, Guest RV, Kendall TJ, Wilson DH, Wojtacha D, Robson AJ, Ridgway RA, Samuel K, Van Rooijen N, Barry ST, Wigmore SJ, Sansom OJ, Forbes SJ. Boulter L, et al. Among authors: wigmore sj. J Clin Invest. 2015 Mar 2;125(3):1269-85. doi: 10.1172/JCI76452. Epub 2015 Feb 17. J Clin Invest. 2015. PMID: 25689248 Free PMC article.
Govert Bidloo's liver: human symmetry reflected.
Guest RV, Margócsy D, Wigmore SJ. Guest RV, et al. Among authors: wigmore sj. Lancet. 2014 Feb 22;383(9918):688-9. doi: 10.1016/s0140-6736(14)60248-8. Lancet. 2014. PMID: 24567974 No abstract available.
CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure.
Stutchfield BM, Antoine DJ, Mackinnon AC, Gow DJ, Bain CC, Hawley CA, Hughes MJ, Francis B, Wojtacha D, Man TY, Dear JW, Devey LR, Mowat AM, Pollard JW, Park BK, Jenkins SJ, Simpson KJ, Hume DA, Wigmore SJ, Forbes SJ. Stutchfield BM, et al. Among authors: wigmore sj. Gastroenterology. 2015 Dec;149(7):1896-1909.e14. doi: 10.1053/j.gastro.2015.08.053. Epub 2015 Sep 5. Gastroenterology. 2015. PMID: 26344055 Free PMC article.
Notch3 drives development and progression of cholangiocarcinoma.
Guest RV, Boulter L, Dwyer BJ, Kendall TJ, Man TY, Minnis-Lyons SE, Lu WY, Robson AJ, Gonzalez SF, Raven A, Wojtacha D, Morton JP, Komuta M, Roskams T, Wigmore SJ, Sansom OJ, Forbes SJ. Guest RV, et al. Among authors: wigmore sj. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12250-12255. doi: 10.1073/pnas.1600067113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791012 Free PMC article.
TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.
Dwyer BJ, Jarman EJ, Gogoi-Tiwari J, Ferreira-Gonzalez S, Boulter L, Guest RV, Kendall TJ, Kurian D, Kilpatrick AM, Robson AJ, O'Duibhir E, Man TY, Campana L, Starkey Lewis PJ, Wigmore SJ, Olynyk JK, Ramm GA, Tirnitz-Parker JEE, Forbes SJ. Dwyer BJ, et al. Among authors: wigmore sj. J Hepatol. 2021 Apr;74(4):860-872. doi: 10.1016/j.jhep.2020.11.018. Epub 2020 Nov 19. J Hepatol. 2021. PMID: 33221352 Free article.
291 results