Pastan I - Search Results

1

P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.

Kioka N, Tsubota J, Kakehi Y, Komano T, Gottesman MM, Pastan I, Ueda K. Kioka N, et al. Among authors: pastan i. Biochem Biophys Res Commun. 1989 Jul 14;162(1):224-31. doi: 10.1016/0006-291x(89)91985-2. Biochem Biophys Res Commun. 1989. PMID: 2568832

2

Use of recombinant P-glycoprotein fragments to produce antibodies to the multidrug transporter.

Tanaka S, Currier SJ, Bruggemann EP, Ueda K, Germann UA, Pastan I, Gottesman MM. Tanaka S, et al. Among authors: pastan i. Biochem Biophys Res Commun. 1990 Jan 15;166(1):180-6. doi: 10.1016/0006-291x(90)91928-l. Biochem Biophys Res Commun. 1990. PMID: 1967936

3

In situ localization of the human multidrug-resistance gene mRNA using thymine-thymine dimerized single-stranded cDNA.

Sugawara I, Koji T, Ueda K, Pastan I, Gottesman MM, Nakane PK, Mori S. Sugawara I, et al. Among authors: pastan i. Jpn J Cancer Res. 1990 Sep;81(9):949-55. doi: 10.1111/j.1349-7006.1990.tb02672.x. Jpn J Cancer Res. 1990. PMID: 1977730 Free PMC article.

4

Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay.

Ueda K, Yamano Y, Kioka N, Kakehi Y, Yoshida O, Gottesman MM, Pastan I, Komano T. Ueda K, et al. Among authors: pastan i. Jpn J Cancer Res. 1989 Nov;80(11):1127-32. doi: 10.1111/j.1349-7006.1989.tb02269.x. Jpn J Cancer Res. 1989. PMID: 2481665 Free PMC article.

5

MDR1 RNA levels in human renal cell carcinomas: correlation with grade and prediction of reversal of doxorubicin resistance by quinidine in tumor explants.

Kanamaru H, Kakehi Y, Yoshida O, Nakanishi S, Pastan I, Gottesman MM. Kanamaru H, et al. Among authors: pastan i. J Natl Cancer Inst. 1989 Jun 7;81(11):844-9. doi: 10.1093/jnci/81.11.844. J Natl Cancer Inst. 1989. PMID: 2724349

6

The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.

Ueda K, Cornwell MM, Gottesman MM, Pastan I, Roninson IB, Ling V, Riordan JR. Ueda K, et al. Among authors: pastan i. Biochem Biophys Res Commun. 1986 Dec 30;141(3):956-62. doi: 10.1016/s0006-291x(86)80136-x. Biochem Biophys Res Commun. 1986. PMID: 2880583

7

Multidrug resistance in human cancer.

Goldstein LJ, Pastan I, Gottesman MM. Goldstein LJ, et al. Among authors: pastan i. Crit Rev Oncol Hematol. 1992;12(3):243-53. doi: 10.1016/1040-8428(92)90057-w. Crit Rev Oncol Hematol. 1992. PMID: 1353966 Review. No abstract available.

8

Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MRD1 gene expression.

Shen DW, Lu YG, Chin KV, Pastan I, Gottesman MM. Shen DW, et al. Among authors: pastan i. J Cell Sci. 1991 Mar;98 ( Pt 3):317-22. doi: 10.1242/jcs.98.3.317. J Cell Sci. 1991. PMID: 1676033

9

New potent verapamil derivatives that reverse multidrug resistance in human renal carcinoma cells and in transgenic mice expressing the human MDR1 gene.

Mickisch GH, Merlino GT, Aiken PM, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. J Urol. 1991 Aug;146(2):447-53. doi: 10.1016/s0022-5347(17)37822-9. J Urol. 1991. PMID: 1677434

10

Chemotherapy and chemosensitization of transgenic mice which express the human multidrug resistance gene in bone marrow: efficacy, potency, and toxicity.

Mickisch GH, Licht T, Merlino GT, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pastan i. Cancer Res. 1991 Oct 1;51(19):5417-24. Cancer Res. 1991. PMID: 1680550

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