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daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans.
Mendler M, Schlotterer A, Ibrahim Y, Kukudov G, Fleming T, Bierhaus A, Riedinger C, Schwenger V, Herzig S, Hecker M, Tyedmers J, Nawroth PP, Morcos M. Mendler M, et al. Among authors: schlotterer a. Diabetologia. 2015 Feb;58(2):393-401. doi: 10.1007/s00125-014-3415-5. Epub 2014 Oct 17. Diabetologia. 2015. PMID: 25322843
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.
Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP. Morcos M, et al. Among authors: schlotterer a. Aging Cell. 2008 Mar;7(2):260-9. doi: 10.1111/j.1474-9726.2008.00371.x. Epub 2008 Jan 21. Aging Cell. 2008. PMID: 18221415 Free article.
C. elegans as model for the study of high glucose- mediated life span reduction.
Schlotterer A, Kukudov G, Bozorgmehr F, Hutter H, Du X, Oikonomou D, Ibrahim Y, Pfisterer F, Rabbani N, Thornalley P, Sayed A, Fleming T, Humpert P, Schwenger V, Zeier M, Hamann A, Stern D, Brownlee M, Bierhaus A, Nawroth P, Morcos M. Schlotterer A, et al. Diabetes. 2009 Nov;58(11):2450-6. doi: 10.2337/db09-0567. Epub 2009 Aug 12. Diabetes. 2009. PMID: 19675139 Free PMC article.
38 results