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CFTR represses a PDX1 axis to govern pancreatic ductal cell fate.
Rotti PG, Yi Y, Gasser G, Yuan F, Sun X, Apak-Evans I, Wu P, Liu G, Choi S, Reeves R, Scioneaux AE, Zhang Y, Winter M, Liang B, Cunicelli N, Uc A, Norris AW, Sussel L, Wells KL, Engelhardt JF. Rotti PG, et al. Among authors: wells kl. iScience. 2024 Nov 15;27(12):111393. doi: 10.1016/j.isci.2024.111393. eCollection 2024 Dec 20. iScience. 2024. PMID: 39687022 Free PMC article.
Transgenic ferret models define pulmonary ionocyte diversity and function.
Yuan F, Gasser GN, Lemire E, Montoro DT, Jagadeesh K, Zhang Y, Duan Y, Ievlev V, Wells KL, Rotti PG, Shahin W, Winter M, Rosen BH, Evans I, Cai Q, Yu M, Walsh SA, Acevedo MR, Pandya DN, Akurathi V, Dick DW, Wadas TJ, Joo NS, Wine JJ, Birket S, Fernandez CM, Leung HM, Tearney GJ, Verkman AS, Haggie PM, Scott K, Bartels D, Meyerholz DK, Rowe SM, Liu X, Yan Z, Haber AL, Sun X, Engelhardt JF. Yuan F, et al. Among authors: wells kl. Nature. 2023 Sep;621(7980):857-867. doi: 10.1038/s41586-023-06549-9. Epub 2023 Sep 20. Nature. 2023. PMID: 37730992 Free PMC article.
Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.
Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L. Abarinov V, et al. Among authors: wells kl. Genes Dev. 2023 Jun 1;37(11-12):490-504. doi: 10.1101/gad.350569.123. Epub 2023 Jun 26. Genes Dev. 2023. PMID: 37364986 Free PMC article.
44 results