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Page 1
Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).
Takahashi H, Riether D, Bartolozzi A, Bosanac T, Berger V, Binetti R, Broadwater J, Chen Z, Crux R, De Lombaert S, Dave R, Dines JA, Fadra-Khan T, Flegg A, Garrigou M, Hao MH, Huber J, Hutzler JM, Kerr S, Kotey A, Liu W, Lo HY, Loke PL, Mahaney PE, Morwick TM, Napier S, Olague A, Pack E, Padyana AK, Thomson DS, Tye H, Wu L, Zindell RM, Abeywardane A, Simpson T. Takahashi H, et al. Among authors: dines ja. J Med Chem. 2015 Feb 26;58(4):1669-90. doi: 10.1021/jm501185j. Epub 2015 Feb 11. J Med Chem. 2015. PMID: 25671290
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).
MacKinnon CH, Lau K, Burch JD, Chen Y, Dines J, Ding X, Eigenbrot C, Heifetz A, Jaochico A, Johnson A, Kraemer J, Kruger S, Krülle TM, Liimatta M, Ly J, Maghames R, Montalbetti CA, Ortwine DF, Pérez-Fuertes Y, Shia S, Stein DB, Trani G, Vaidya DG, Wang X, Bromidge SM, Wu LC, Pei Z. MacKinnon CH, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6331-5. doi: 10.1016/j.bmcl.2013.09.069. Epub 2013 Oct 1. Bioorg Med Chem Lett. 2013. PMID: 24138940
Optoelectronic Systems Based on InGaAs- Complementary-Metal-Oxide-Semiconductor Smart-Pixel Arrays and Free-Space Optical Interconnects.
Walker AC, Yang TY, Gourlay J, Dines JA, Forbes MG, Prince SM, Baillie DA, Neilson DT, Williams R, Wilkinson LC, Smith GR, Desmulliez MP, Buller GS, Taghizadeh MR, Waddie A, Underwood I, Stanley CR, Pottier F, Vögele B, Sibbett W. Walker AC, et al. Among authors: dines ja. Appl Opt. 1998 May 10;37(14):2822-30. doi: 10.1364/ao.37.002822. Appl Opt. 1998. PMID: 18273228
Perfect-shuffle interconnected bitonic sorter: optoelectronic design.
Desmulliez MP, Tooley FA, Dines JA, Grant NL, Goodwill DJ, Baillie D, Wherrett BS, Foulk PW, Ashcroft S, Black P. Desmulliez MP, et al. Among authors: dines ja. Appl Opt. 1995 Aug 10;34(23):5077-90. doi: 10.1364/AO.34.005077. Appl Opt. 1995. PMID: 21052353