Kandel S - Search Results

1

Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.

Basudhar D, Madrona Y, Kandel S, Lampe JN, Nishida CR, de Montellano PR. Basudhar D, et al. Among authors: kandel s. J Biol Chem. 2015 Apr 17;290(16):10000-17. doi: 10.1074/jbc.M114.627935. Epub 2015 Feb 10. J Biol Chem. 2015. PMID: 25670859 Free PMC article.

2

Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity.

Kandel SE, Lampe JN. Kandel SE, et al. Chem Res Toxicol. 2014 Sep 15;27(9):1474-86. doi: 10.1021/tx500203s. Epub 2014 Aug 29. Chem Res Toxicol. 2014. PMID: 25133307 Free PMC article. Review.

3

Cytochrome P450 Enzyme Metabolites in Lead Discovery and Development.

Kandel SE, Wienkers LC, Lampe JN. Kandel SE, et al. Annu Rep Med Chem. 2014;49:347-359. doi: 10.1016/B978-0-12-800167-7.00022-5. Annu Rep Med Chem. 2014. PMID: 25797999 Free PMC article.

4

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.

Kandel SE, Han LW, Mao Q, Lampe JN. Kandel SE, et al. Drug Metab Dispos. 2017 Dec;45(12):1266-1275. doi: 10.1124/dmd.117.078055. Epub 2017 Oct 6. Drug Metab Dispos. 2017. PMID: 28986474 Free PMC article.

5

Inhibition of CYP3A7 DHEA-S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates.

Kandel SE, Lampe JN. Kandel SE, et al. Chem Res Toxicol. 2021 Apr 19;34(4):1150-1160. doi: 10.1021/acs.chemrestox.1c00028. Epub 2021 Apr 6. Chem Res Toxicol. 2021. PMID: 33821626 Free PMC article.

6

Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening.

Work HM, Kandel SE, Lampe JN. Work HM, et al. Sci Rep. 2021 Sep 30;11(1):19443. doi: 10.1038/s41598-021-98219-x. Sci Rep. 2021. PMID: 34593846 Free PMC article.

7

Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE.

Tooker BC, Kandel SE, Work HM, Lampe JN. Tooker BC, et al. J Biol Chem. 2022 Mar;298(3):101629. doi: 10.1016/j.jbc.2022.101629. Epub 2022 Jan 24. J Biol Chem. 2022. PMID: 35085556 Free PMC article.

8

Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (M^pro) inhibitors.

Hicks EG, Kandel SE, Lampe JN. Hicks EG, et al. Bioorg Med Chem Lett. 2022 Jun 15;66:128732. doi: 10.1016/j.bmcl.2022.128732. Epub 2022 Apr 12. Bioorg Med Chem Lett. 2022. PMID: 35427739 Free PMC article.

9

Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement.

Hvizdak M, Kandel SE, Work HM, Gracey EG, McCullough RL, Lampe JN. Hvizdak M, et al. J Inorg Biochem. 2023 Mar;240:112120. doi: 10.1016/j.jinorgbio.2023.112120. Epub 2023 Jan 4. J Inorg Biochem. 2023. PMID: 36638633 Free PMC article.

10

Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.

Liu J, Kandel SE, Lampe JN, Scott EE. Liu J, et al. J Biol Chem. 2023 Aug;299(8):104993. doi: 10.1016/j.jbc.2023.104993. Epub 2023 Jun 29. J Biol Chem. 2023. PMID: 37392852 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

276 results

Search Page

Filters