Ojima I - Search Results

1

Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Elmes MW, et al. Among authors: ojima i. J Biol Chem. 2015 Apr 3;290(14):8711-21. doi: 10.1074/jbc.M114.618447. Epub 2015 Feb 9. J Biol Chem. 2015. PMID: 25666611 Free PMC article.

2

Discovery of anti-TB agents that target the cell-division protein FtsZ.

Kumar K, Awasthi D, Berger WT, Tonge PJ, Slayden RA, Ojima I. Kumar K, et al. Among authors: ojima i. Future Med Chem. 2010 Aug;2(8):1305-23. doi: 10.4155/fmc.10.220. Future Med Chem. 2010. PMID: 21339840 Free PMC article. Review.

3

Tumor-targeting drug delivery of new-generation taxoids.

Ojima I, Zuniga ES, Berger WT, Seitz JD. Ojima I, et al. Future Med Chem. 2012 Jan;4(1):33-50. doi: 10.4155/fmc.11.167. Future Med Chem. 2012. PMID: 22168163 Free PMC article. Review.

4

Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.

Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Berger WT, et al. Among authors: ojima i. PLoS One. 2012;7(12):e50968. doi: 10.1371/journal.pone.0050968. Epub 2012 Dec 7. PLoS One. 2012. PMID: 23236415 Free PMC article.

5

Crystallographic study of FABP5 as an intracellular endocannabinoid transporter.

Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Sanson B, et al. Among authors: ojima i. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):290-8. doi: 10.1107/S1399004713026795. Epub 2014 Jan 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24531463 Free PMC article.

6

Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia.

Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. Kaczocha M, et al. Among authors: ojima i. PLoS One. 2014 Apr 4;9(4):e94200. doi: 10.1371/journal.pone.0094200. eCollection 2014. PLoS One. 2014. PMID: 24705380 Free PMC article.

7

Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A.

Teng YH, Berger WT, Nesbitt NM, Kumar K, Balius TE, Rizzo RC, Tonge PJ, Ojima I, Swaminathan S. Teng YH, et al. Among authors: ojima i. Bioorg Med Chem. 2015 Sep 1;23(17):5489-95. doi: 10.1016/j.bmc.2015.07.040. Epub 2015 Jul 27. Bioorg Med Chem. 2015. PMID: 26275678

8

Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms.

Peng X, Studholme K, Kanjiya MP, Luk J, Bogdan D, Elmes MW, Carbonetti G, Tong S, Gary Teng YH, Rizzo RC, Li H, Deutsch DG, Ojima I, Rebecchi MJ, Puopolo M, Kaczocha M. Peng X, et al. Among authors: ojima i. Mol Pain. 2017 Jan;13:1744806917697007. doi: 10.1177/1744806917697007. Mol Pain. 2017. PMID: 28326944 Free PMC article.

9

The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites.

Hsu HC, Tong S, Zhou Y, Elmes MW, Yan S, Kaczocha M, Deutsch DG, Rizzo RC, Ojima I, Li H. Hsu HC, et al. Among authors: ojima i. Biochemistry. 2017 Jul 11;56(27):3454-3462. doi: 10.1021/acs.biochem.7b00194. Epub 2017 Jun 28. Biochemistry. 2017. PMID: 28632393 Free PMC article.

10

Fatty acid-binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation.

Bogdan D, Falcone J, Kanjiya MP, Park SH, Carbonetti G, Studholme K, Gomez M, Lu Y, Elmes MW, Smietalo N, Yan S, Ojima I, Puopolo M, Kaczocha M. Bogdan D, et al. Among authors: ojima i. J Biol Chem. 2018 Apr 6;293(14):5295-5306. doi: 10.1074/jbc.RA118.001593. Epub 2018 Feb 13. J Biol Chem. 2018. PMID: 29440395 Free PMC article.

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