Young C - Search Results

1

Store-operated calcium entry contributes to abnormal Ca²⁺ signalling in dystrophic mdx mouse myoblasts.

Onopiuk M, Brutkowski W, Young C, Krasowska E, Róg J, Ritso M, Wojciechowska S, Arkle S, Zabłocki K, Górecki DC. Onopiuk M, et al. Among authors: young c. Arch Biochem Biophys. 2015 Mar 1;569:1-9. doi: 10.1016/j.abb.2015.01.025. Epub 2015 Feb 4. Arch Biochem Biophys. 2015. PMID: 25659883

2

P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment.

Young CN, Brutkowski W, Lien CF, Arkle S, Lochmüller H, Zabłocki K, Górecki DC. Young CN, et al. J Cell Mol Med. 2012 May;16(5):1026-37. doi: 10.1111/j.1582-4934.2011.01397.x. J Cell Mol Med. 2012. PMID: 21794079 Free PMC article.

3

A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.

Young CN, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, Gorecki DC. Young CN, et al. Autophagy. 2015;11(1):113-30. doi: 10.4161/15548627.2014.994402. Autophagy. 2015. PMID: 25700737 Free PMC article.

4

Co-delivery of indoleamine 2,3-dioxygenase prevents loss of expression of an antigenic transgene in dystrophic mouse muscles.

Sharma D, Al-Khalidi R, Edgar S, An Q, Wang Y, Young C, Nowis D, Gorecki DC. Sharma D, et al. Among authors: young c. Gene Ther. 2017 Feb;24(2):113-119. doi: 10.1038/gt.2016.82. Epub 2016 Dec 22. Gene Ther. 2017. PMID: 28004656

5

Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition.

Young CNJ, Chira N, Róg J, Al-Khalidi R, Benard M, Galas L, Chan P, Vaudry D, Zablocki K, Górecki DC. Young CNJ, et al. J Mol Cell Biol. 2018 Jun 1;10(3):229-242. doi: 10.1093/jmcb/mjx030. J Mol Cell Biol. 2018. PMID: 28992079

6

Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism.

Al-Khalidi R, Panicucci C, Cox P, Chira N, Róg J, Young CNJ, McGeehan RE, Ambati K, Ambati J, Zabłocki K, Gazzerro E, Arkle S, Bruno C, Górecki DC. Al-Khalidi R, et al. Among authors: young cnj. Acta Neuropathol Commun. 2018 Apr 11;6(1):27. doi: 10.1186/s40478-018-0530-4. Acta Neuropathol Commun. 2018. PMID: 29642926 Free PMC article.

7

Total Absence of Dystrophin Expression Exacerbates Ectopic Myofiber Calcification and Fibrosis and Alters Macrophage Infiltration Patterns.

Young CNJ, Gosselin MRF, Rumney R, Oksiejuk A, Chira N, Bozycki L, Matryba P, Łukasiewicz K, Kao AP, Dunlop J, Robson SC, Zabłocki K, Górecki DC. Young CNJ, et al. Am J Pathol. 2020 Jan;190(1):190-205. doi: 10.1016/j.ajpath.2019.09.021. Epub 2019 Nov 11. Am J Pathol. 2020. PMID: 31726040 Free article.

8

P2RX7 Purinoceptor as a Therapeutic Target-The Second Coming?

Young CNJ, Górecki DC. Young CNJ, et al. Front Chem. 2018 Jun 28;6:248. doi: 10.3389/fchem.2018.00248. eCollection 2018. Front Chem. 2018. PMID: 30003075 Free PMC article. Review.

9

Purinergic receptors in skeletal muscles in health and in muscular dystrophy.

Krasowska E, Róg J, Sinadinos A, Young CN, Górecki DC, Zabłocki K. Krasowska E, et al. Among authors: young cn. Postepy Biochem. 2014;60(4):483-9. Postepy Biochem. 2014. PMID: 25807827 Review.

10

P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy.

Sinadinos A, Young CN, Al-Khalidi R, Teti A, Kalinski P, Mohamad S, Floriot L, Henry T, Tozzi G, Jiang T, Wurtz O, Lefebvre A, Shugay M, Tong J, Vaudry D, Arkle S, doRego JC, Górecki DC. Sinadinos A, et al. Among authors: young cn. PLoS Med. 2015 Oct 13;12(10):e1001888. doi: 10.1371/journal.pmed.1001888. eCollection 2015 Oct. PLoS Med. 2015. PMID: 26461208 Free PMC article.

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