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Page 1
Epigenetics in idiopathic pulmonary fibrosis.
Tzouvelekis A, Kaminski N. Tzouvelekis A, et al. Biochem Cell Biol. 2015 Apr;93(2):159-70. doi: 10.1139/bcb-2014-0126. Epub 2015 Jan 13. Biochem Cell Biol. 2015. PMID: 25659821 Review.
SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.
Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N. Tzouvelekis A, et al. Am J Respir Crit Care Med. 2017 Feb 15;195(4):500-514. doi: 10.1164/rccm.201602-0329OC. Am J Respir Crit Care Med. 2017. PMID: 27736153 Free PMC article.
Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis.
Ryu C, Sun H, Gulati M, Herazo-Maya JD, Chen Y, Osafo-Addo A, Brandsdorfer C, Winkler J, Blaul C, Faunce J, Pan H, Woolard T, Tzouvelekis A, Antin-Ozerkis DE, Puchalski JT, Slade M, Gonzalez AL, Bogenhagen DF, Kirillov V, Feghali-Bostwick C, Gibson K, Lindell K, Herzog RI, Dela Cruz CS, Mehal W, Kaminski N, Herzog EL, Trujillo G. Ryu C, et al. Among authors: tzouvelekis a. Am J Respir Crit Care Med. 2017 Dec 15;196(12):1571-1581. doi: 10.1164/rccm.201612-2480OC. Am J Respir Crit Care Med. 2017. PMID: 28783377 Free PMC article.
Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study.
Herazo-Maya JD, Sun J, Molyneaux PL, Li Q, Villalba JA, Tzouvelekis A, Lynn H, Juan-Guardela BM, Risquez C, Osorio JC, Yan X, Michel G, Aurelien N, Lindell KO, Klesen MJ, Moffatt MF, Cookson WO, Zhang Y, Garcia JGN, Noth I, Prasse A, Bar-Joseph Z, Gibson KF, Zhao H, Herzog EL, Rosas IO, Maher TM, Kaminski N. Herazo-Maya JD, et al. Among authors: tzouvelekis a. Lancet Respir Med. 2017 Nov;5(11):857-868. doi: 10.1016/S2213-2600(17)30349-1. Epub 2017 Sep 21. Lancet Respir Med. 2017. PMID: 28942086 Free PMC article.
Pulmonary hypertension in patients with interstitial lung disease.
Karampitsakos T, Tzouvelekis A, Chrysikos S, Bouros D, Tsangaris I, Fares WH. Karampitsakos T, et al. Among authors: tzouvelekis a. Pulm Pharmacol Ther. 2018 Jun;50:38-46. doi: 10.1016/j.pupt.2018.03.002. Epub 2018 Mar 29. Pulm Pharmacol Ther. 2018. PMID: 29605286 Review.
S100A12 as a marker of worse cardiac output and mortality in pulmonary hypertension.
Tzouvelekis A, Herazo-Maya JD, Ryu C, Chu JH, Zhang Y, Gibson KF, Adonteng-Boateng PK, Li Q, Pan H, Cherry B, Ahmad F, Ford HJ, Herzog EL, Kaminski N, Fares WH. Tzouvelekis A, et al. Respirology. 2018 Aug;23(8):771-779. doi: 10.1111/resp.13302. Epub 2018 Apr 2. Respirology. 2018. PMID: 29611244 Free PMC article.
Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis.
Xylourgidis N, Min K, Ahangari F, Yu G, Herazo-Maya JD, Karampitsakos T, Aidinis V, Binzenhöfer L, Bouros D, Bennett AM, Kaminski N, Tzouvelekis A. Xylourgidis N, et al. Among authors: tzouvelekis a. Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L678-L689. doi: 10.1152/ajplung.00264.2018. Epub 2019 Sep 4. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31483681 Free PMC article.
Transcriptional regulatory model of fibrosis progression in the human lung.
McDonough JE, Ahangari F, Li Q, Jain S, Verleden SE, Herazo-Maya J, Vukmirovic M, DeIuliis G, Tzouvelekis A, Tanabe N, Chu F, Yan X, Verschakelen J, Homer RJ, Manatakis DV, Zhang J, Ding J, Maes K, De Sadeleer L, Vos R, Neyrinck A, Benos PV, Bar-Joseph Z, Tantin D, Hogg JC, Vanaudenaerde BM, Wuyts WA, Kaminski N. McDonough JE, et al. Among authors: tzouvelekis a. JCI Insight. 2019 Nov 14;4(22):e131597. doi: 10.1172/jci.insight.131597. JCI Insight. 2019. PMID: 31600171 Free PMC article.
An allosteric site on MKP5 reveals a strategy for small-molecule inhibition.
Gannam ZTK, Min K, Shillingford SR, Zhang L, Herrington J, Abriola L, Gareiss PC, Pantouris G, Tzouvelekis A, Kaminski N, Zhang X, Yu J, Jamali H, Ellman JA, Lolis E, Anderson KS, Bennett AM. Gannam ZTK, et al. Among authors: tzouvelekis a. Sci Signal. 2020 Aug 25;13(646):eaba3043. doi: 10.1126/scisignal.aba3043. Sci Signal. 2020. PMID: 32843541 Free PMC article.
237 results