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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Konermann S, et al. Among authors: zhang f. Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10. Nature. 2015. PMID: 25494202 Free PMC article.
In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Ran FA, et al. Among authors: zhang f. Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1. Nature. 2015. PMID: 25830891 Free PMC article.
High-throughput functional genomics using CRISPR-Cas9.
Shalem O, Sanjana NE, Zhang F. Shalem O, et al. Among authors: zhang f. Nat Rev Genet. 2015 May;16(5):299-311. doi: 10.1038/nrg3899. Epub 2015 Apr 9. Nat Rev Genet. 2015. PMID: 25854182 Free PMC article. Review.
CRISPR germline engineering--the community speaks.
Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q. Bosley KS, et al. Among authors: zhang f. Nat Biotechnol. 2015 May;33(5):478-86. doi: 10.1038/nbt.3227. Nat Biotechnol. 2015. PMID: 25965754 No abstract available.
CRISPR-Cas9: Prospects and Challenges.
Zhang F. Zhang F. Hum Gene Ther. 2015 Jul;26(7):409-10. doi: 10.1089/hum.2015.29002.fzh. Hum Gene Ther. 2015. PMID: 26176430 Free PMC article. No abstract available.
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.
Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, Zhang F, Hacohen N, Regev A. Parnas O, et al. Among authors: zhang f. Cell. 2015 Jul 30;162(3):675-86. doi: 10.1016/j.cell.2015.06.059. Epub 2015 Jul 16. Cell. 2015. PMID: 26189680 Free PMC article.
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. Canver MC, et al. Among authors: zhang f. Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16. Nature. 2015. PMID: 26375006 Free PMC article.
Applications of CRISPR-Cas systems in neuroscience.
Heidenreich M, Zhang F. Heidenreich M, et al. Among authors: zhang f. Nat Rev Neurosci. 2016 Jan;17(1):36-44. doi: 10.1038/nrn.2015.2. Epub 2015 Dec 10. Nat Rev Neurosci. 2016. PMID: 26656253 Free PMC article. Review.
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