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Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans.
Cadicamo CD, Mortier J, Wolber G, Hell M, Heinrich IE, Michel D, Semlin L, Berger U, Korting HC, Höltje HD, Koksch B, Borelli C. Cadicamo CD, et al. Among authors: wolber g. Biochem Pharmacol. 2013 Apr 1;85(7):881-7. doi: 10.1016/j.bcp.2012.12.008. Epub 2012 Dec 21. Biochem Pharmacol. 2013. PMID: 23262278
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
Ottanà R, Maccari R, Mortier J, Caselli A, Amuso S, Camici G, Rotondo A, Wolber G, Paoli P. Ottanà R, et al. Among authors: wolber g. Eur J Med Chem. 2014 Jan;71:112-27. doi: 10.1016/j.ejmech.2013.11.001. Epub 2013 Nov 11. Eur J Med Chem. 2014. PMID: 24287560
In silico virtual screening approaches for anti-viral drug discovery.
Murgueitio MS, Bermudez M, Mortier J, Wolber G. Murgueitio MS, et al. Among authors: wolber g. Drug Discov Today Technol. 2012 Autumn;9(3):e219-25. doi: 10.1016/j.ddtec.2012.07.009. Drug Discov Today Technol. 2012. PMID: 24990575 Free PMC article.
Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity.
Galal SA, Khairat SH, Ragab FA, Abdelsamie AS, Ali MM, Soliman SM, Mortier J, Wolber G, El Diwani HI. Galal SA, et al. Among authors: wolber g. Eur J Med Chem. 2014 Oct 30;86:122-32. doi: 10.1016/j.ejmech.2014.08.048. Epub 2014 Aug 15. Eur J Med Chem. 2014. PMID: 25147154
220 results