Opal P - Search Results

1

The promise and perils of HDAC inhibitors in neurodegeneration.

Didonna A, Opal P. Didonna A, et al. Among authors: opal p. Ann Clin Transl Neurol. 2015 Jan;2(1):79-101. doi: 10.1002/acn3.147. Epub 2014 Dec 3. Ann Clin Transl Neurol. 2015. PMID: 25642438 Free PMC article. Review.

2

Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation.

Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. Mahammad S, et al. Among authors: opal p. J Clin Invest. 2013 May;123(5):1964-75. doi: 10.1172/JCI66387. Epub 2013 Apr 15. J Clin Invest. 2013. PMID: 23585478 Free PMC article.

3

The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1.

Venkatraman A, Hu YS, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, Opal P. Venkatraman A, et al. Among authors: opal p. Hum Mol Genet. 2014 Jul 15;23(14):3733-45. doi: 10.1093/hmg/ddu081. Epub 2014 Mar 4. Hum Mol Genet. 2014. PMID: 24594842 Free PMC article.

4

Paraneoplastic cerebellar degeneration with anti-Yo antibodies - a review.

Venkatraman A, Opal P. Venkatraman A, et al. Among authors: opal p. Ann Clin Transl Neurol. 2016 Jun 30;3(8):655-63. doi: 10.1002/acn3.328. eCollection 2016 Aug. Ann Clin Transl Neurol. 2016. PMID: 27606347 Free PMC article. Review.

5

Advances in Sequencing Technologies for Understanding Hereditary Ataxias: A Review.

Didonna A, Opal P. Didonna A, et al. Among authors: opal p. JAMA Neurol. 2016 Dec 1;73(12):1485-1490. doi: 10.1001/jamaneurol.2016.3097. JAMA Neurol. 2016. PMID: 27749953 Free PMC article. Review.

6

Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.

Edamakanti CR, Do J, Didonna A, Martina M, Opal P. Edamakanti CR, et al. Among authors: opal p. J Clin Invest. 2018 Jun 1;128(6):2252-2265. doi: 10.1172/JCI96765. Epub 2018 Apr 23. J Clin Invest. 2018. PMID: 29533923 Free PMC article.

7

Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes.

Frederick NM, Shah PV, Didonna A, Langley MR, Kanthasamy AG, Opal P. Frederick NM, et al. Among authors: opal p. Hum Mol Genet. 2019 Apr 15;28(8):1343-1356. doi: 10.1093/hmg/ddy433. Hum Mol Genet. 2019. PMID: 30590536 Free PMC article.

8

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders.

Didonna A, Opal P. Didonna A, et al. Among authors: opal p. Mol Neurodegener. 2019 May 16;14(1):19. doi: 10.1186/s13024-019-0318-4. Mol Neurodegener. 2019. PMID: 31097008 Free PMC article. Review.

9

Spinocerebellar ataxia clinical trials: opportunities and challenges.

Brooker SM, Edamakanti CR, Akasha SM, Kuo SH, Opal P. Brooker SM, et al. Among authors: opal p. Ann Clin Transl Neurol. 2021 Jul;8(7):1543-1556. doi: 10.1002/acn3.51370. Epub 2021 May 21. Ann Clin Transl Neurol. 2021. PMID: 34019331 Free PMC article. Review.

10

Pharmacological perturbation reveals deficits in D2 receptor responses in Thap1 null mice.

Frederick NM, Pooler MM, Shah P, Didonna A, Opal P. Frederick NM, et al. Among authors: opal p. Ann Clin Transl Neurol. 2021 Dec;8(12):2302-2308. doi: 10.1002/acn3.51481. Epub 2021 Nov 21. Ann Clin Transl Neurol. 2021. PMID: 34802187 Free PMC article.

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