Gautam P - Search Results

1

Endothelial destabilization by angiopoietin-2 via integrin β1 activation.

Hakanpaa L, Sipila T, Leppanen VM, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P. Hakanpaa L, et al. Among authors: gautam p. Nat Commun. 2015 Jan 30;6:5962. doi: 10.1038/ncomms6962. Nat Commun. 2015. PMID: 25635707 Free PMC article.

2

Donor simvastatin treatment prevents ischemia-reperfusion and acute kidney injury by preserving microvascular barrier function.

Tuuminen R, Nykänen AI, Saharinen P, Gautam P, Keränen MA, Arnaudova R, Rouvinen E, Helin H, Tammi R, Rilla K, Krebs R, Lemström KB. Tuuminen R, et al. Among authors: gautam p. Am J Transplant. 2013 Aug;13(8):2019-34. doi: 10.1111/ajt.12315. Epub 2013 Jun 14. Am J Transplant. 2013. PMID: 23773358 Free article.

3

Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects.

Julkunen H, Cichonska A, Gautam P, Szedmak S, Douat J, Pahikkala T, Aittokallio T, Rousu J. Julkunen H, et al. Among authors: gautam p. Nat Commun. 2020 Dec 1;11(1):6136. doi: 10.1038/s41467-020-19950-z. Nat Commun. 2020. PMID: 33262326 Free PMC article.

4

A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening.

Gupta A, Gautam P, Wennerberg K, Aittokallio T. Gupta A, et al. Among authors: gautam p. Commun Biol. 2020 Jan 23;3(1):42. doi: 10.1038/s42003-020-0765-z. Commun Biol. 2020. PMID: 31974521 Free PMC article.

5

Prediction of drug combination effects with a minimal set of experiments.

Ianevski A, Giri AK, Gautam P, Kononov A, Potdar S, Saarela J, Wennerberg K, Aittokallio T. Ianevski A, et al. Among authors: gautam p. Nat Mach Intell. 2019 Dec;1(12):568-577. doi: 10.1038/s42256-019-0122-4. Epub 2019 Dec 9. Nat Mach Intell. 2019. PMID: 32368721 Free PMC article.

6

Consistency in drug response profiling.

Mpindi JP, Yadav B, Östling P, Gautam P, Malani D, Murumägi A, Hirasawa A, Kangaspeska S, Wennerberg K, Kallioniemi O, Aittokallio T. Mpindi JP, et al. Among authors: gautam p. Nature. 2016 Nov 30;540(7631):E5-E6. doi: 10.1038/nature20171. Nature. 2016. PMID: 27905421 No abstract available.

7

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.

Szwajda A, Gautam P, Karhinen L, Jha SK, Saarela J, Shakyawar S, Turunen L, Yadav B, Tang J, Wennerberg K, Aittokallio T. Szwajda A, et al. Among authors: gautam p. Chem Biol. 2015 Aug 20;22(8):1144-55. doi: 10.1016/j.chembiol.2015.06.021. Epub 2015 Jul 23. Chem Biol. 2015. PMID: 26211361

8

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.

Gautam P, Karhinen L, Szwajda A, Jha SK, Yadav B, Aittokallio T, Wennerberg K. Gautam P, et al. Mol Cancer. 2016 May 10;15(1):34. doi: 10.1186/s12943-016-0517-3. Mol Cancer. 2016. PMID: 27165605 Free PMC article.

9

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.

Tang J, Tanoli ZU, Ravikumar B, Alam Z, Rebane A, Vähä-Koskela M, Peddinti G, van Adrichem AJ, Wakkinen J, Jaiswal A, Karjalainen E, Gautam P, He L, Parri E, Khan S, Gupta A, Ali M, Yetukuri L, Gustavsson AL, Seashore-Ludlow B, Hersey A, Leach AR, Overington JP, Repasky G, Wennerberg K, Aittokallio T. Tang J, et al. Among authors: gautam p. Cell Chem Biol. 2018 Feb 15;25(2):224-229.e2. doi: 10.1016/j.chembiol.2017.11.009. Epub 2017 Dec 21. Cell Chem Biol. 2018. PMID: 29276046 Free PMC article.

10

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.

Gautam P, Jaiswal A, Aittokallio T, Al-Ali H, Wennerberg K. Gautam P, et al. Cell Chem Biol. 2019 Jul 18;26(7):970-979.e4. doi: 10.1016/j.chembiol.2019.03.011. Epub 2019 May 2. Cell Chem Biol. 2019. PMID: 31056464 Free PMC article.

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