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Page 1
Targets for therapy in sarcomeric cardiomyopathies.
Tardiff JC, Carrier L, Bers DM, Poggesi C, Ferrantini C, Coppini R, Maier LS, Ashrafian H, Huke S, van der Velden J. Tardiff JC, et al. Among authors: carrier l. Cardiovasc Res. 2015 Apr 1;105(4):457-70. doi: 10.1093/cvr/cvv023. Epub 2015 Jan 29. Cardiovasc Res. 2015. PMID: 25634554 Free PMC article. Review.
Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction.
van Dijk SJ, Dooijes D, dos Remedios C, Michels M, Lamers JM, Winegrad S, Schlossarek S, Carrier L, ten Cate FJ, Stienen GJ, van der Velden J. van Dijk SJ, et al. Among authors: carrier l. Circulation. 2009 Mar 24;119(11):1473-83. doi: 10.1161/CIRCULATIONAHA.108.838672. Epub 2009 Mar 9. Circulation. 2009. PMID: 19273718
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L. Mearini G, et al. Among authors: carrier l. Cardiovasc Res. 2010 Jan 15;85(2):357-66. doi: 10.1093/cvr/cvp348. Epub 2009 Oct 22. Cardiovasc Res. 2010. PMID: 19850579 Free PMC article.
Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.
Boontje NM, Merkus D, Zaremba R, Versteilen A, de Waard MC, Mearini G, de Beer VJ, Carrier L, Walker LA, Niessen HW, Dobrev D, Stienen GJ, Duncker DJ, van der Velden J. Boontje NM, et al. Among authors: carrier l. J Mol Cell Cardiol. 2011 Mar;50(3):487-99. doi: 10.1016/j.yjmcc.2010.12.002. Epub 2010 Dec 13. J Mol Cell Cardiol. 2011. PMID: 21156182 Free article.
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function.
van Dijk SJ, Paalberends ER, Najafi A, Michels M, Sadayappan S, Carrier L, Boontje NM, Kuster DW, van Slegtenhorst M, Dooijes D, dos Remedios C, ten Cate FJ, Stienen GJ, van der Velden J. van Dijk SJ, et al. Among authors: carrier l. Circ Heart Fail. 2012 Jan;5(1):36-46. doi: 10.1161/CIRCHEARTFAILURE.111.963702. Epub 2011 Dec 16. Circ Heart Fail. 2012. PMID: 22178992 Free article.
GSK3β phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: short communication.
Kuster DW, Sequeira V, Najafi A, Boontje NM, Wijnker PJ, Witjas-Paalberends ER, Marston SB, Dos Remedios CG, Carrier L, Demmers JA, Redwood C, Sadayappan S, van der Velden J. Kuster DW, et al. Among authors: carrier l. Circ Res. 2013 Feb 15;112(4):633-9. doi: 10.1161/CIRCRESAHA.112.275602. Epub 2012 Dec 31. Circ Res. 2013. PMID: 23277198 Free PMC article.
Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J. Sequeira V, et al. Among authors: carrier l. Circ Res. 2013 May 24;112(11):1491-505. doi: 10.1161/CIRCRESAHA.111.300436. Epub 2013 Mar 18. Circ Res. 2013. PMID: 23508784 Free PMC article.
261 results