Kos J - Search Results

1

Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties.

Guzior N, Bajda M, Skrok M, Kurpiewska K, Lewiński K, Brus B, Pišlar A, Kos J, Gobec S, Malawska B. Guzior N, et al. Among authors: kos j. Eur J Med Chem. 2015 Mar 6;92:738-49. doi: 10.1016/j.ejmech.2015.01.027. Epub 2015 Jan 13. Eur J Med Chem. 2015. PMID: 25621991

2

Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.

Jevnikar Z, Obermajer N, Doljak B, Turk S, Gobec S, Svajger U, Hailfinger S, Thome M, Kos J. Jevnikar Z, et al. Among authors: kos j. J Leukoc Biol. 2011 Jul;90(1):99-109. doi: 10.1189/jlb.1110622. Epub 2011 Mar 31. J Leukoc Biol. 2011. PMID: 21454358

3

Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds.

Mirković B, Renko M, Turk S, Sosič I, Jevnikar Z, Obermajer N, Turk D, Gobec S, Kos J. Mirković B, et al. Among authors: kos j. ChemMedChem. 2011 Aug 1;6(8):1351-6. doi: 10.1002/cmdc.201100098. Epub 2011 May 20. ChemMedChem. 2011. PMID: 21598397 No abstract available.

4

Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B.

Sosič I, Mirković B, Turk S, Štefaneb B, Kos J, Gobec S. Sosič I, et al. Among authors: kos j. Eur J Med Chem. 2011 Sep;46(9):4648-56. doi: 10.1016/j.ejmech.2011.08.005. Epub 2011 Aug 9. Eur J Med Chem. 2011. PMID: 21849222

5

Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

Mirković B, Sosič I, Gobec S, Kos J. Mirković B, et al. Among authors: kos j. PLoS One. 2011;6(11):e27197. doi: 10.1371/journal.pone.0027197. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22073285 Free PMC article.

6

Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives.

Sosič I, Mirković B, Arenz K, Stefane B, Kos J, Gobec S. Sosič I, et al. Among authors: kos j. J Med Chem. 2013 Jan 24;56(2):521-33. doi: 10.1021/jm301544x. Epub 2013 Jan 4. J Med Chem. 2013. PMID: 23252745

7

C-terminal peptide of γ-enolase impairs amyloid-β-induced apoptosis through p75(NTR) signaling.

Pišlar AH, Kos J. Pišlar AH, et al. Among authors: kos j. Neuromolecular Med. 2013 Sep;15(3):623-35. doi: 10.1007/s12017-013-8247-9. Epub 2013 Jul 11. Neuromolecular Med. 2013. PMID: 23842744

8

Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.

Pišlar AH, Zidar N, Kikelj D, Kos J. Pišlar AH, et al. Among authors: kos j. Neuropharmacology. 2014 Jul;82:121-31. doi: 10.1016/j.neuropharm.2013.07.040. Epub 2013 Aug 16. Neuropharmacology. 2014. PMID: 23958447

9

Cysteine cathepsins in neurological disorders.

Pišlar A, Kos J. Pišlar A, et al. Among authors: kos j. Mol Neurobiol. 2014 Apr;49(2):1017-30. doi: 10.1007/s12035-013-8576-6. Epub 2013 Nov 15. Mol Neurobiol. 2014. PMID: 24234234 Review.

10

Intracellular signaling by cathepsin X: molecular mechanisms and diagnostic and therapeutic opportunities in cancer.

Kos J, Vižin T, Fonović UP, Pišlar A. Kos J, et al. Semin Cancer Biol. 2015 Apr;31:76-83. doi: 10.1016/j.semcancer.2014.05.001. Epub 2014 May 14. Semin Cancer Biol. 2015. PMID: 24835450 Review.

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