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Loss of BAP1 function leads to EZH2-dependent transformation.
LaFave LM, Béguelin W, Koche R, Teater M, Spitzer B, Chramiec A, Papalexi E, Keller MD, Hricik T, Konstantinoff K, Micol JB, Durham B, Knutson SK, Campbell JE, Blum G, Shi X, Doud EH, Krivtsov AV, Chung YR, Khodos I, de Stanchina E, Ouerfelli O, Adusumilli PS, Thomas PM, Kelleher NL, Luo M, Keilhack H, Abdel-Wahab O, Melnick A, Armstrong SA, Levine RL. LaFave LM, et al. Among authors: kelleher nl. Nat Med. 2015 Nov;21(11):1344-9. doi: 10.1038/nm.3947. Epub 2015 Oct 5. Nat Med. 2015. PMID: 26437366 Free PMC article.
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".
LaFave LM, Béguelin W, Koche R, Teater M, Spitzer B, Chramiec A, Papalexi E, Keller MD, Hricik T, Konstantinoff K, Micol JB, Durham B, Knutson SK, Campbell JE, Blum G, Shi X, Doud EH, Krivtsov AV, Chung YR, Khodos I, de Stanchina E, Ouerfelli O, Adusumilli PS, Thomas PM, Kelleher NL, Luo M, Keilhack H, Abdel-Wahab O, Melnick A, Armstrong SA, Levine RL. LaFave LM, et al. Among authors: kelleher nl. Nat Med. 2016 Jun 7;22(6):578-9. doi: 10.1038/nm.4094. Nat Med. 2016. PMID: 27270773 No abstract available.
Characterization of Methanobactin from Methylosinus sp. LW4.
Kenney GE, Goering AW, Ross MO, DeHart CJ, Thomas PM, Hoffman BM, Kelleher NL, Rosenzweig AC. Kenney GE, et al. Among authors: kelleher nl. J Am Chem Soc. 2016 Sep 7;138(35):11124-7. doi: 10.1021/jacs.6b06821. Epub 2016 Aug 26. J Am Chem Soc. 2016. PMID: 27527063 Free PMC article.
Substrate Trapping in the Siderophore Tailoring Enzyme PvdQ.
Clevenger KD, Mascarenhas R, Catlin D, Wu R, Kelleher NL, Drake EJ, Gulick AM, Liu D, Fast W. Clevenger KD, et al. Among authors: kelleher nl. ACS Chem Biol. 2017 Mar 17;12(3):643-647. doi: 10.1021/acschembio.7b00031. Epub 2017 Feb 15. ACS Chem Biol. 2017. PMID: 28186406 Free PMC article.
445 results