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664 results

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Real-time resolution of point mutations that cause phenovariance in mice.
Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, Shi H, Wang J, Sun L, SoRelle J, McAlpine W, Hutchins N, Zhan X, Fina M, Gobert R, Quan J, Kreutzer M, Arnett S, Hawkins K, Leach A, Tate C, Daniel C, Reyna C, Prince L, Davis S, Purrington J, Bearden R, Weatherly J, White D, Russell J, Sun Q, Tang M, Li X, Scott L, Moresco EM, McInerney GM, Karlsson Hedestam GB, Xie Y, Beutler B. Wang T, et al. Among authors: leach a. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E440-9. doi: 10.1073/pnas.1423216112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605905 Free PMC article.
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells.
Aurora AB, Khivansara V, Leach A, Gill JG, Martin-Sandoval M, Yang C, Kasitinon SY, Bezwada D, Tasdogan A, Gu W, Mathews TP, Zhao Z, DeBerardinis RJ, Morrison SJ. Aurora AB, et al. Among authors: leach a. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120617119. doi: 10.1073/pnas.2120617119. Proc Natl Acad Sci U S A. 2022. PMID: 35110412 Free PMC article.
Mitochondrial complex I promotes kidney cancer metastasis.
Bezwada D, Perelli L, Lesner NP, Cai L, Brooks B, Wu Z, Vu HS, Sondhi V, Cassidy DL, Kasitinon S, Kelekar S, Cai F, Aurora AB, Patrick M, Leach A, Ghandour R, Zhang Y, Do D, McDaniel P, Sudderth J, Dumesnil D, House S, Rosales T, Poole AM, Lotan Y, Woldu S, Bagrodia A, Meng X, Cadeddu JA, Mishra P, Garcia-Bermudez J, Pedrosa I, Kapur P, Courtney KD, Malloy CR, Genovese G, Margulis V, DeBerardinis RJ. Bezwada D, et al. Among authors: leach a. Nature. 2024 Sep;633(8031):923-931. doi: 10.1038/s41586-024-07812-3. Epub 2024 Aug 14. Nature. 2024. PMID: 39143213 Free PMC article.
Mitochondrial metabolism in primary and metastatic human kidney cancers.
Bezwada D, Lesner NP, Brooks B, Vu HS, Wu Z, Cai L, Kasitinon S, Kelekar S, Cai F, Aurora AB, Patrick M, Leach A, Ghandour R, Zhang Y, Do D, Sudderth J, Dumesnil D, House S, Rosales T, Poole AM, Lotan Y, Woldu S, Bagrodia A, Meng X, Cadeddu JA, Mishra P, Pedrosa I, Kapur P, Courtney KD, Malloy CR, Margulis V, DeBerardinis RJ. Bezwada D, et al. Among authors: leach a. bioRxiv [Preprint]. 2023 Feb 7:2023.02.06.527285. doi: 10.1101/2023.02.06.527285. bioRxiv. 2023. Update in: Nature. 2024 Sep;633(8031):923-931. doi: 10.1038/s41586-024-07812-3 PMID: 36798172 Free PMC article. Updated. Preprint.
Lower respiratory tract infections following respiratory syncytial virus monoclonal antibody nirsevimab immunization versus placebo: Analysis from a Phase 3 randomized clinical trial (MELODY).
Arbetter D, Gopalakrishnan V, Aksyuk AA, Ahani B, Chang Y, Dagan R, Esser MT, Hammitt LL, Mankad VS, Saez-Llorens X, Shen D, Leach A, Kelly EJ, Villafana T, Wilkins D. Arbetter D, et al. Among authors: leach a. Clin Infect Dis. 2024 Dec 4:ciae596. doi: 10.1093/cid/ciae596. Online ahead of print. Clin Infect Dis. 2024. PMID: 39656748
Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.
Tredup C, Ackloo S, Beck H, Brown PJ, Bullock AN, Ciulli A, Dikic I, Edfeldt K, Edwards AM, Elkins JM, Farin HF, Fon EA, Gstaiger M, Günther J, Gustavsson AL, Häberle S, Isigkeit L, Huber KVM, Kotschy A, Krämer O, Leach AR, Marsden BD, Matsui H, Merk D, Montel F, Mulder MPC, Müller S, Owen DR, Proschak E, Röhm S, Stolz A, Sundström M, von Delft F, Willson TM, Arrowsmith CH, Knapp S. Tredup C, et al. Among authors: leach ar. RSC Med Chem. 2024 Nov 29. doi: 10.1039/d4md00735b. Online ahead of print. RSC Med Chem. 2024. PMID: 39618964 Free PMC article.
Epidemiologic and genomic characterization of an outbreak of Rift Valley fever among humans and dairy cattle in northern Tanzania.
Madut DB, Rubach MP, Allan KJ, Thomas KM, de Glanville WA, Halliday JEB, Costales C, Carugati M, Rolfe RJ, Bonnewell JP, Maze MJ, Mremi AR, Amsi PT, Kalengo NH, Lyamuya F, Kinabo GD, Mbwasi R, Kilonzo KG, Maro VP, Mmbaga BT, Lwezaula B, Mosha C, Marandu A, Kibona TJ, Zhu F, Chawla T, Chia WN, Anderson DE, Wang LF, Liu J, Houpt ER, Martines RB, Zaki SR, Leach A, Gibbons A, Chiang CF, Patel K, Klena JD, Cleaveland S, Crump JA. Madut DB, et al. Among authors: leach a. J Infect Dis. 2024 Nov 13:jiae562. doi: 10.1093/infdis/jiae562. Online ahead of print. J Infect Dis. 2024. PMID: 39535803
Daily glycome and transcriptome profiling reveals polysaccharide structures and correlated glycosyltransferases critical for cotton fiber growth.
Swaminathan S, Grover CE, Mugisha AS, Sichterman LE, Lee Y, Yang P, Mallery EL, Jareczek JJ, Leach AG, Xie J, Wendel JF, Szymanski DB, Zabotina OA. Swaminathan S, et al. Among authors: leach ag. Plant J. 2024 Dec;120(5):1857-1879. doi: 10.1111/tpj.17084. Epub 2024 Oct 23. Plant J. 2024. PMID: 39441672 Free PMC article.
664 results