Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins.
Poruchynsky MS, Komlodi-Pasztor E, Trostel S, Wilkerson J, Regairaz M, Pommier Y, Zhang X, Kumar Maity T, Robey R, Burotto M, Sackett D, Guha U, Fojo AT.
Poruchynsky MS, et al. Among authors: burotto m.
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1571-6. doi: 10.1073/pnas.1416418112. Epub 2015 Jan 20.
Proc Natl Acad Sci U S A. 2015.
PMID: 25605897
Free PMC article.